Relationship Between Biofilm Formation and Antimicrobial Resistance in Gram-Negative Bacteria

Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease
Virginio CepasSara M Soto

Abstract

Gram-negative microorganisms are a significant cause of infection in both community and nosocomial settings. The increase, emergence, and spread of antimicrobial resistance among bacteria are the most important health problems worldwide. One of the mechanisms of resistance used by bacteria is biofilm formation, which is also a mechanism of virulence. This study analyzed the possible relationship between antimicrobial resistance and biofilm formation among isolates of three Gram-negative bacteria species. Several relationships were found between the ability to form biofilm and antimicrobial resistance, being different for each species. Indeed, gentamicin and ceftazidime resistance was related to biofilm formation in Escherichia coli, piperacillin/tazobactam, and colistin in Klebsiella pneumoniae, and ciprofloxacin in Pseudomonas aeruginosa. However, no relationship was observed between global resistance or multidrug-resistance and biofilm formation. In addition, compared with other reported data, the isolates in the present study showed higher rates of antimicrobial resistance. In conclusion, the acquisition of specific antimicrobial resistance can compromise or enhance biofilm formation in several species of Gram-negative bacte...Continue Reading

References

Feb 15, 2001·JAMA : the Journal of the American Medical Association·G H Cassell, J Mekalanos
Apr 5, 2002·Clinical Microbiology Reviews·Rodney M Donlan, J William Costerton
Aug 10, 2005·Seminars in Respiratory and Critical Care Medicine·Didier GuillemotPatrice Courvalin
Aug 27, 2005·Nature·Lucas R HoffmanSamuel I Miller
Jun 10, 2010·Annual Review of Microbiology·Kim Lewis
Oct 12, 2010·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Alexander J Kallen, Arjun Srinivasan
Oct 12, 2010·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Louis B Rice
Nov 19, 2011·The International Journal of Artificial Organs·Jeffrey B Kaplan
Jan 18, 2013·Journal of Global Infectious Diseases·Monil SinghaiRajeev Goyal
Apr 8, 2014·The Journal of Antimicrobial Chemotherapy·Anna FàbregaJordi Vila
May 18, 2017·International Journal of Molecular Sciences·Enea Gino Di DomenicoFabrizio Ensoli

❮ Previous
Next ❯

Citations

Apr 28, 2020·Current Topics in Medicinal Chemistry·Bruno CasciaroMaria Luisa Mangoni
Sep 11, 2020·International Journal of Microbiology·Gedif Meseret Abebe
Dec 29, 2020·Environmental Pollution·Huizhong LiuQingshan Shi
Jan 26, 2021·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Martin KrátkýJarmila Vinšová
Dec 29, 2020·Frontiers in Cellular and Infection Microbiology·Enea Gino Di DomenicoFabrizio Ensoli
Jan 29, 2021·Infection and Drug Resistance·Fengjuan TianYigang Tong
Feb 26, 2021·Journal of Applied Microbiology·N B S SilvaD D B Röder
Apr 12, 2021·Carbohydrate Polymers·Lisa Myrseth HemmingsenNataša Škalko-Basnet
Jun 12, 2021·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Katarzyna ĆwiekAlina Wieliczko
Jul 6, 2021·International Journal of Microbiology·Kiana KarimiLeili Shokoohizadeh
Aug 18, 2021·Cell Host & Microbe·Eric M BrownRamnik J Xavier
Sep 17, 2020·ACS Applied Materials & Interfaces·Valerie Ortiz-GómezEduardo Nicolau
Jul 24, 2021·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Francisco Javier CandelAntonio Oliver
Oct 27, 2021·Advanced Drug Delivery Reviews·Sajid AsgharThierry F Vandamme
Nov 11, 2021·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Ali GoudarztalejerdiMostafa Mohammad Mirzaei
Dec 7, 2021·Frontiers in Microbiology·Shravani S BobdeMonique L Van Hoek
Dec 16, 2021·Water Environment Research : a Research Publication of the Water Environment Federation·Debaraj BhattacharyyaSamiran Bandyopadhyay

❮ Previous
Next ❯

Software Mentioned

SPSS
GraphPad Prism

Related Concepts

Related Feeds

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Biofilm & Infectious Disease

Biofilm formation is a key virulence factor for a wide range of microorganisms that cause chronic infections.Here is the latest research on biofilm and infectious diseases.

Biofilms

Biofilms are adherent bacterial communities embedded in a polymer matrix and can cause persistent human infections that are highly resistant to antibiotics. Discover the latest research on Biofilms here.

CRISPR Screens in Drug Resistance

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of CRISPR-Cas system in high-throughput genome-wide screens to identify genes that may confer drug resistance.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.