Relationship Between Body Mass Index and Outcomes Among Hospitalized Patients With Community-Acquired Pneumonia

The Journal of Infectious Diseases
Anna M BramleyCenters for Disease Control and Prevention Etiology of Pneumonia in the Community (EPIC) Study Team

Abstract

The effect of body mass index (BMI) on community-acquired pneumonia (CAP) severity is unclear. We investigated the relationship between BMI and CAP outcomes (hospital length of stay [LOS], intensive care unit [ICU] admission, and invasive mechanical ventilation) in hospitalized CAP patients from the Centers for Disease Control and Prevention Etiology of Pneumonia in the Community (EPIC) study, adjusting for age, demographics, underlying conditions, and smoking status (adults only). Compared with normal-weight children, odds of ICU admission were higher in children who were overweight (adjusted odds ratio [aOR], 1.7; 95% confidence interval [CI], 1.1-2.8) or obese (aOR, 2.1; 95% CI, 1.4-3.2), and odds of mechanical ventilation were higher in children with obesity (aOR, 2.7; 95% CI, 1.3-5.6). When stratified by asthma (presence/absence), these findings remained significant only in children with asthma. Compared with normal-weight adults, odds of LOS >3 days were higher in adults who were underweight (aOR, 1.6; 95% CI, 1.1-2.4), and odds of mechanical ventilation were lowest in adults who were overweight (aOR, 0.5; 95% CI, .3-.9). Children who were overweight or obese, particularly those with asthma, had higher odds of ICU admissi...Continue Reading

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Citations

Feb 23, 2018·Current Opinion in Pulmonary Medicine·Julio A Ramirez
Jun 21, 2018·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Takuto TakahashiScott Miller
Oct 25, 2020·Hospital Pediatrics·Kathryn E KylerJessica L Bettenhausen
Jul 21, 2020·Obesity Research & Clinical Practice·Hao WangDahlia Hassani
Oct 12, 2020·The American Journal of Emergency Medicine·Seok Hoon KoKi Young Jeong
Oct 2, 2021·Hospital Pediatrics·Kathryn E KylerJennifer L Goldman

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