Relationship between brain perfusion computed tomography variables and cerebral perfusion pressure in severe head trauma patients

Critical Care Medicine
M WintermarkP Maeder

Abstract

To compare brain perfusion-computed tomography (CT) results with invasive cerebral perfusion pressure (CPP) monitoring in severe head trauma patients. Prospective cohort study. Emergency room and surgical intensive care unit of our hospital. Sixty-one severe head trauma patients. We prospectively collected 103 perfusion-CT examinations with simultaneous measurement of mean arterial pressure and intracranial pressure, affording calculation of CPP. The statistical relationship between perfusion-CT results and the corresponding CPP values was evaluated using Wilcoxon (Mann-Whitney) and generalized F-tests. The functional outcome of the 61 patients was evaluated 3 months after trauma on the basis of the Glasgow Outcome Scale score and compared between groups using Fisher's exact tests. Perfusion-CT enabled us to distinguish between two groups of patients. Within each group, a significant correlation (p <.001) between the CPP values and the corresponding perfusion-CT results was demonstrated. There was also a significant correlation (p <.001) between the CPP values and the extent of the abnormal perfusion-CT areas (R up to.817). The first group was characterized by a weak dependence of perfusion-CT results on the corresponding CPP v...Continue Reading

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Citations

Nov 28, 2007·Neuroradiology·Jean F SoustielMenashe Zaaroor
May 12, 2005·Annales Françaises D'anesthèsie Et De Rèanimation·G AudibertP-M Mertes
Jan 21, 2006·Journal of Neuroradiology. Journal De Neuroradiologie·M WintermarkH Yonas
Jul 27, 2011·Journal of Neurotrauma·Jill V HunterBarbara A Holshouser
May 23, 2006·Critical Care Medicine·Paul M Vespa
Sep 1, 2013·Anesthesia, Essays and Researches·Charu MahajanParmod Kumar Bithal
Nov 26, 2013·Journal of Neurosurgery·Abel Po-Hao HuangMax Wintermark
Oct 10, 2015·AJNR. American Journal of Neuroradiology·A S TammUNKNOWN ICH ADAPT Investigators
Aug 22, 2013·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Nathalie SalaMauro Oddo
May 10, 2008·Journal of Neuroradiology. Journal De Neuroradiologie·M WintermarkJ D Chien
Mar 11, 2006·Journal of Neuroradiology. Journal De Neuroradiologie·M WintermarkP Schnyder
Sep 4, 2010·Journal of Magnetic Resonance Imaging : JMRI·E Mark HaackeDouglas H Smith
May 17, 2006·Annales Françaises D'anesthèsie Et De Rèanimation·J-F PayenJ-F Le Bas
Nov 27, 2014·AJNR. American Journal of Neuroradiology·M WintermarkUNKNOWN American College of Radiology Head Injury Institute
Jan 27, 2012·Neurologia Medico-chirurgica·Minoru ShigemoriUNKNOWN Guidelines Committee on the Management of Severe Head Injury, Japan Society of Neurotraumatology
Nov 5, 2005·AACN Clinical Issues·Catherine J Kirkness
Aug 16, 2005·Stroke; a Journal of Cerebral Circulation·Max WintermarkHoward Yonas
Mar 15, 2006·Current Opinion in Anaesthesiology·François Girard
Jan 4, 2017·International Journal of Molecular Sciences·Bàrbara Laviña
Oct 4, 2020·The Journal of Trauma and Acute Care Surgery·Jernej AvsenikKatarina Šurlan Popović
Jul 19, 2021·Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine·Djino KhakiJohan Ljungqvist

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