PMID: 16633225Apr 25, 2006Paper

Relationship between central corneal thickness and localized retinal nerve fiber layer defect in normal-tension glaucoma

Journal of Glaucoma
Hyuk Jin ChoiSeung-Sik Hwang

Abstract

To determine whether central corneal thickness (CCT) is related to the extent of localized retinal nerve fiber layer (RNFL) defect at the initial examination of normal-tension glaucoma (NTG) patients. Seventy-five eyes of 75 NTG patients showing localized RNFL defects on RNFL photographs and corresponding visual field defects at the initial visit to a glaucoma specialist were selected for this study. All participants completed refraction, Goldmann applanation tonometry, CCT measurement, stereoscopic disc photography, RNFL photography, and automated perimetry. Each patient's age, spherical equivalent, intraocular pressure, CCT, approximation of the RNFL defect to the fovea (angle alpha), circumferential width of the RNFL defects (angle beta), horizontal and vertical cup-to-disc ratios, and mean deviation of visual field were analyzed. In univariate and multivariate analyses, lower CCT was significantly associated with increased horizontal and vertical cup-to-disc ratios, decreased angle alpha, and increased angle beta. For a decrease of 10 microm of CCT, horizontal and vertical cup-to-disc ratios increased by 0.020, angle alpha decreased by 1.58 degrees, and angle beta increased by 1.71 degrees, respectively. CCT is a significan...Continue Reading

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Citations

Oct 15, 2013·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Kelechi C Ogbuehi, Uchechukwu L Osuagwu
Jul 29, 2008·American Journal of Ophthalmology·Tarkan MumcuogluUNKNOWN Advanced Imaging in Glaucoma Study Group
Sep 15, 2011·Acta Ophthalmologica·Tetsuya MoritaKimiya Shimizu
Nov 22, 2019·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Elena NutterovaJan Lestak
Jun 15, 2007·Current Opinion in Ophthalmology

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