Abstract
Inflammatory molecules play a role in the development of atherosclerosis, which is the primary origin of cardiovascular disorders. However, to the best of our knowledge, no study has attempted to investigate the relationship between these circulating molecules and the prediction of cardiovascular risk. The present study aimed to investigate the relationships of vascular cell adhesion molecule-1, intercellular adhesion molecule-1, E-selectin and matrix metalloproteinase 9 serum concentrations with the extent of coronary lesions. Seventy-four individuals who were undergoing coronary angiography for the first time for diagnostic purposes were enrolled in this study. The extent of the coronary lesion was assessed using the Friesinger Index, and subjects were classified into four groups: no lesions, minor lesions, intermediate lesions and major lesions. Serum biochemical parameters and serum concentrations of vascular cell adhesion molecule-1, intercellular adhesion molecule-1, E-selectin and matrix metalloproteinase 9 were analyzed. The vascular cell adhesion molecule-1 concentration was higher than 876 ng/mL in individuals with intermediate and major lesions (p<0.001 and p=0.020, respectively). Moreover, logistic regression analys...Continue Reading
References
Jun 1, 1983·The Journal of Clinical Investigation·I RingqvistD Fray
Aug 1, 1995·Circulation·E FalkV Fuster
Aug 4, 2007·Arteriosclerosis, Thrombosis, and Vascular Biology·Elena Galkina, Klaus Ley
Apr 28, 2009·The Journal of Surgical Research·Carlos A MurilloGlenn C Hunter
Jul 17, 2009·Clinics·Angela Bacelar Albuquerque BampiProtásio Lemos da Luz
Oct 12, 2010·Anadolu Kardiyoloji Dergisi : AKD = the Anatolian Journal of Cardiology·Serdar BayataMehmet Köseoğlu
Nov 16, 2012·Coronary Artery Disease·Ko-Fan WangShing-Jong Lin
Jul 25, 2013·Atherosclerosis·Patrícia ChagasCarla Helena Augustin Schwanke
Mar 22, 2014·Arteriosclerosis, Thrombosis, and Vascular Biology·Jin M ChengIsabella Kardys
Apr 20, 2014·Physiological Reports·Velidi H RaoDevendra K Agrawal
Jul 2, 2014·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·J-F DilméL Vila
Jul 19, 2014·Archives of Medical Research·Maria Elena SotoLuis Eduardo Juárez-Orozco
Feb 1, 2015·Matrix Biology : Journal of the International Society for Matrix Biology·Andrew C Newby
May 23, 2015·Thrombosis and Haemostasis·Matthias HokeGeorg Goliasch
May 29, 2015·Clinics·Arif YükselGiray Bozkaya
Jun 29, 2015·Archives of Medical Research·Marco Antonio Peña-DuqueEduardo A Arias-Sánchez
Aug 9, 2015·Atherosclerosis·Kenneth M BorowR Preston Mason
Dec 2, 2015·Experimental and Therapeutic Medicine·Wei MuQichong Xing
Jan 23, 2016·Radiology Research and Practice·Sunny GoelOn Chen
May 3, 2016·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Weslley Santiago AndradeJose Augusto Soares Barreto-Filho
Sep 3, 2016·Lipids in Health and Disease·Mychelle Kytchia Rodrigues Nunes DuarteVivian Nogueira Silbiger
Citations
Apr 3, 2020·Arteriosclerosis, Thrombosis, and Vascular Biology·Shoko Ohura-KajitaniHiroaki Shimokawa
Feb 23, 2019·Aging·Ying ZhuTong Zhang
Jun 23, 2020·Journal of Cardiovascular Pharmacology·Jie YuYan Wang
Jul 6, 2020·Internal and Emergency Medicine·Andrea PiccioniFrancesco Franceschi
May 12, 2019·Scientific Reports·Victor Hugo Rezende DuarteVivian Nogueira Silbiger
Oct 29, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Daciele Paola PreciAndréia Machado Cardoso
Mar 2, 2021·ACS Omega·Min SongYan Yang
May 15, 2021·Biomarkers in Medicine·Ane Km NériIgor P Saraiva