Relationship between comorbidity and asthma control

Archivos de bronconeumología
Luis Alejandro Pérez De LlanoProyecto Camaron (Control del Asma Mediante el Análisis Regular del Óxido Nítrico)

Abstract

The coexistence of potentially aggravating processes is common in asthmatics, particularly in patients with difficult control. The primary aim of this study is to ascertain whether comorbidity id more common in uncontrolled patients. As a secondary aim, we propose to evaluate the correlation between the asthma control test (ACT) and the fraction of exhaled nitric oxide (FENO). A prospective, observational study comparing the function and clinical picture of two groups of asthmatics: controlled (ACT≥20) and uncontrolled (ACT<20). They were all assessed for, smoking, rhinosinusitis, obesity, anxiety, depression, vocal cord dysfunction, gastro-oesophageal reflux (GORD), allergic bronchopulmonary aspergillosis (ABPA), COPD and nasal polyps. A total of 50 patients with controlled asthma and 102 with suboptimal control were included. The patients with an ACT≥20 had better lung function, less variation in PEF, less bronchial hyper-reactivity and lower FENO values. Comorbidities were found in 95% of the controlled asthmatics and in 97% of the uncontrolled. Only the presence of nasal polyps, GORD and ABPA was more frequent in the uncontrolled group. However, the simultaneous presence of 3 or more comorbidity factors was significantly mo...Continue Reading

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Citations

Dec 11, 2013·BMC Pulmonary Medicine·Jose Gregorio Soto-CamposUNKNOWN Grupo Emergente de Asma (GEA) del Área de Asma de la SEPAR
Dec 4, 2012·Medicina clínica·José A GullónGema Castaño
Oct 25, 2012·Revista clínica española·C Cisneros Serrano
Apr 5, 2011·Archivos de bronconeumología·Adalberto Pacheco-GalvánAlyn H Morice
Nov 9, 2016·The European Respiratory Journal·Wenjia ChenUNKNOWN Canadian Respiratory Research Network
May 15, 2013·Journal of Breath Research·Enrico HefflerGiovanni Rolla
Sep 19, 2020·International Journal of Chronic Obstructive Pulmonary Disease·Luis Pérez de LlanoBorja G Cosio
Jun 4, 2015·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Wenjia ChenMohsen Sadatsafavi
Mar 20, 2021·Journal of Asthma and Allergy·Luis Pérez de LlanoIrene Martin Robles
Feb 9, 2011·Archivos de bronconeumología·Isabel Urrutia LandaAntolín López-Viña

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