Relationship between Dietary Approaches to Stop Hypertension score and Alternative Healthy Eating Index score with plasma asymmetrical dimethylarginine levels in patients referring for coronary angiography

Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association
Zeinab MokhtariJavad Nasrollahzadeh

Abstract

Asymmetrical dimethyl arginine (ADMA) is a competitive inhibitor in the production of nitric oxide (NO) from arginine and NO plays an important role in the preservation of vascular dilation. Elevated ADMA is a strong predictive factor for coronary artery disease (CAD). Dietary Approaches to Stop Hypertension (DASH) and Alternative Healthy Eating Index (AHEI) patterns contain factors that may influence plasma ADMA levels. The present study examined the association between the DASH score and AHEI score with plasma ADMA concentration in people with suspected heart disease selected for coronary angiography. This cross-sectional study was conducted in 148 people aged 40-80 years who were referred for coronary angiography. The DASH diet score and AHEI score were calculated for each individual based on food groups. Plasma ADMA levels were measured by high-performance liquid chromatography. ADMA concentrations were higher in the CAD group compared to the non-CAD group [0.98 (0.37) μmol L(-1) compared to 0.84 (0.42) μmol L(-1) ; P = 0.02]. There was a significant negative association between the quartile DASH score and ADMA concentration (standardised β = -0.172, P = 0.038). The ADMA concentration was lower in patients who were at the h...Continue Reading

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Citations

Feb 16, 2017·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Golaleh AsghariFereidoun Azizi
Dec 20, 2018·Nutrition & Metabolism·Golaleh AsghariFereidoun Azizi

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