PMID: 7336574Jan 1, 1981Paper

Relationship between diseases of the pancreas and hyperplasia of Brunner's glands

Virchows Archiv. A, Pathological Anatomy and Histology
M StolteH Prestele

Abstract

Examination of 105 duodeno-pancreatectomy specimens showed that 75% of the cases of chronic pancreatitis (n = 74) manifested diffuse hyperplasia of Brunner's glands. In pancreatitis involving part of the pancreas in the presence of ducts of the embryonic type (n = 6), in segmental pancreatitis (n = 16), and in pancreatic cancer (n = 23), no significant difference in the thickness of the layer of Brunner's glands was found as compared with normal specimens. There was no statistically significant correlation between the degree of hyperplasia of Brunner's glands and the degree of scarring of the exocrine pancreatic parenchyma. Nor was there any correlation between existence and extent of scarring of the duodenal wall, inflammatory infiltration of the duodenal mucosa, duration of disease, consumption of alcohol and history of gall stones and ulcers in patients with and without hyperplasia of Brunner's glands. Diffuse hyperplasia of the duodenal glands is probably an adaptive reaction to the exocrine insufficiency of the pancreas or the changes in gastric function (hyperacidity, accelerated emptying of the stomach) caused by chronic pancreatitis. A fact which supports this statement is that the inhibitor hormone urogastrone--an inhi...Continue Reading

References

Jan 1, 1977·Scandinavian Journal of Gastroenterology·L E HanssenJ Myren
Oct 13, 1973·Lancet·R F HarveyA E Read
Dec 1, 1969·Proceedings of the Society for Experimental Biology and Medicine·R S Jones, A D Hall
Nov 1, 1965·Annals of Internal Medicine·R E Kravetz, H M Spiro
Jan 1, 1956·Annals of Internal Medicine·M D DEREN, P D HENRY
Oct 1, 1958·Physiological Reviews·M L GROSSMAN
Apr 1, 1959·The British Journal of Radiology·V BERMAN, M J GOLDBERG
Jul 1, 1959·A.M.A. Archives of Surgery·B G STREETE, F E STULL
Aug 6, 1959·The New England Journal of Medicine·K W WARREN, R B CATTELL
Sep 1, 1963·Gut·O FITZGERALDS J BOLAND
Oct 1, 1943·Annals of Surgery·L R Dragstedt

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Citations

Dec 16, 2006·Digestive Diseases and Sciences·Reina OhbaSumio Watanabe
Dec 17, 1998·Journal of Clinical Gastroenterology·J ZangaraG Fantry
Dec 2, 2011·The Journal of Small Animal Practice·E J BowenS J Baines
May 18, 2013·Journal of Veterinary Internal Medicine·A KullmannR C Smedley
Mar 1, 1992·American Journal of Surgery·K Yamaguchi, M Tanaka
Aug 23, 2006·Gastrointestinal Endoscopy·Padmini KrishnamurthyN Gopalswamy
Feb 17, 2017·Case Reports in Gastroenterology·Michele SorletoCarsten Gartung
Jul 26, 2011·Journal of Fish Biology·M D Renkawitz, T F Sheehan
Dec 1, 2001·Gastrointestinal Endoscopy·C H ChenC L Kuo
Jul 27, 2006·Pancreas·Vilma Salvatori ChappuisHanifa Bouzourene
Oct 16, 2010·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·A Kumar, R Shane Tubbs
Sep 8, 2020·Diabetologia·Michael R RickelsRebecca L Hull
Jul 1, 1997·Cancer Control : Journal of the Moffitt Cancer Center·D Coppola, R C Karl
Jun 13, 2019·Canadian Journal of Gastroenterology & Hepatology·Sabahattin Destek, Vahit Onur Gul
Dec 15, 2020·Diagnostic Cytopathology·Domenika Ortiz RequenaMonica Garcia-Buitrago
Apr 30, 2021·Advances in Therapy·Menghua ZhuXingshun Qi

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