Relationship between double-cuff versus single-cuff peritoneal dialysis catheters and risk of peritonitis

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
Sharon J NessimSarbjit V Jassal

Abstract

Peritonitis among peritoneal dialysis (PD) patients remains an important complication. To date, no catheter type has consistently been shown to reduce peritonitis risk. It has been hypothesized that double-cuff catheters might be superior to single-cuff catheters in preventing peritonitis caused by periluminal entry of organisms. Using data collected in the multicentre Canadian Baxter Peritonitis Organism Exit-Sites Tunnel Infections (POET) database between 1996 and 2005, the association between number of catheter cuffs and peritonitis was tested. Variables adjusted for in the negative binomial model included age, gender, race, diabetes, renal disease, transfer from haemodialysis, previous renal transplant, PD modality and swan neck versus straight catheter. Data were available for 4247 incident patients with a total of 2555 peritonitis episodes, corresponding to a peritonitis rate of 0.364 per dialysis year at risk. After adjustment for covariates, double-cuff catheter use was associated with a trend towards a lower peritonitis rate ratio (RR) 0.90, 95% confidence interval (CI) 0.80-1.01, P = 0.08]. This trend was largely due to a decreased Staphylococcus aureus peritonitis rate in those with a double-cuff catheter (RR 0.46, 9...Continue Reading

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Citations

Jul 3, 2013·Wiener medizinische Wochenschrift·Gerd R SilberhumerFerdinand Mühlbacher
Apr 23, 2014·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Yeoungjee Cho, David W Johnson
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Nov 22, 2011·Advances in Chronic Kidney Disease·Ramapriya Sinnakirouchenan, Jean L Holley
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Dec 19, 2014·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Benjamin ShiffJeffrey Perl
Jun 11, 2016·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Philip Kam-Tao LiDavid W Johnson
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Sep 7, 2020·Advances in Chronic Kidney Disease·Ali I GardeziRajeev Narayan

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