Relationship between endothelial dependent vasodilation and size of abdominal aortic aneurysms

Annals of Vascular Surgery
Francisco MedinaFrancisco Acin

Abstract

Flow-mediated dilation of the brachial artery (FMDB) indirectly reflects the action of nitric oxide liberated by the endothelium. In patients with abdominal aortic aneurysms (AAA), the changes in nitric oxide metabolism in close association with inflammation, appear to play a leading role in the aetiopathology of this disease, although it is still not clear. The objective was to study the correlation and behavior of FMDB relative to the aneurysm diameter (AD). To evaluate the relationship between C-reactive protein (CRP) and the FMDB in these patients. To study the correlation and behavior of FMDB relative to the aneurysm diameter (AD). To evaluate the relationship between C-reactive protein (CRP) and the FMDB in these patients. The FMDB value and the CRP were determined in a total of 30 patients with an AAA > or =30 mm, confirmed by computed tomography. The cardiovascular and treatment history was recorded, together with the lipid and renal profile and leucocyte count. The median AD in the sample was 43 mm (25 percentile: 37 mm; 75 percentile: 60 mm). The primary variables of the study, FMDB and CRP, were the only ones that differed statistically when we stratified the sample according to AD quartiles (p < 0.001). There was a ...Continue Reading

References

May 1, 1991·Annals of Vascular Surgery·C M BrophyM D Tilson
Jul 15, 1995·The American Journal of Cardiology·L M HarrisJ J Ricotta
Nov 1, 1996·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·A WillsP R Bell
Feb 21, 2002·Journal of Vascular Surgery·Brian S KnippGilbert R Upchurch
Jun 17, 2004·Circulation·Jean Davignon, Peter Ganz
Jun 26, 2004·Journal of Vascular Surgery·Joel E Barbato, Edith Tzeng
Dec 5, 2008·Angiology·Francisco José Medina MaldonadoFrancisco Acín García

❮ Previous
Next ❯

Citations

Aug 19, 2014·The British Journal of Surgery·P W StatherM J Bown
Jun 27, 2012·Redox Report : Communications in Free Radical Research·J PincemailN Sakalihasan
Feb 22, 2012·The Tohoku Journal of Experimental Medicine·Aytun ÇangaÖmer Satiroğlu
Jul 5, 2017·Journal of Atherosclerosis and Thrombosis·Kirthi BellamkondaRegent Lee
Sep 25, 2017·American Journal of Physiology. Heart and Circulatory Physiology·Tom G BaileyChristopher D Askew

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aneurysm

Aneurysms are outward distensions or bulges that occurs in a weakened wall of blood vessels. Discover the latest research on aneurysms here.

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.

Cardiovascular Inflammation

Inflammation plays a significant role in the development of cardiovascular diseases, an understanding of these endogenous processes is critical for evaluating the risks and potential treatment strategies. Discover the latest research on cardiovascular inflammation here.

Aortic Aneurysm

An aortic aneurysm is the weakening and bulging of the blood vessel wall in the aorta. This causes dilatation of the aorta, which is usually asymptomatic but carries the risk of rupture and hemorrhage. Find the latest research on aortic aneurysms here.

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

© 2021 Meta ULC. All rights reserved