Relationship between fatigue after acquired brain injury and depression, injury localization and aetiology: An explorative study in a rehabilitation setting

Journal of Rehabilitation Medicine
Anna HolmqvistMarika C Möller

Abstract

Fatigue after acquired brain injury may be related to the subcortico-frontal attention network. Depression is also strongly related to fatigue. This study investigates whether injury localization, diagnosis and depression are related to self-rated mental fatigue in patients with an acquired brain injury. Retrospective cross-sectional cohort study. Sixty-one patients diagnosed with stroke, subarachnoidal haemorrhage, traumatic brain injury, or brain tumour were included in the study. Patients who underwent a multidisciplinary team assessment during September 2011 to June 2012, and who were assessed with the Mental Fatigue Scale, were included in the study. A significantly higher number of patients with posterior and non-specific lesions experienced fatigue compared with those with subcortical/frontal injuries. Fewer stroke patients experienced fatigue compared with the other patient groups. How-ever, after logistic regression, only depression remained as an explanatory variable for self-rated fatigue. Nevertheless, although all patients with depression were fatigued, not all fatigued patients were depressed. Although depression explains a high degree of fatigue after an acquired brain injury, mental fatigue after brain injury sh...Continue Reading

Citations

Jun 15, 2019·Stroke; a Journal of Cerebral Circulation·Maurizio Paciaroni, Monica Acciarresi
Sep 18, 2020·F1000Research·Ghazaleh AaliFarhad Shokraneh

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