PMID: 7333708Dec 1, 1981Paper

Relationship between fibrin clot retraction and tumorigenesis in C3H/10T1/2 cells

International Journal of Cancer. Journal International Du Cancer
B AzzaroneA Macieira-Coelho

Abstract

Fibrin clot retraction (FCR) was studied in C3H/10T1/2 murine fibroblasts. These cells were able to induce FCR with high efficiency during resting phase as well as during active growth. C3H/10/T1/2 cells which became tumorigenic after X-irradiation lacked FCR activity. Non-tumorigenic revertant clones regained the capacity to induce FCR, while revertants which progressively back-reverted to the neoplastic state showed intermediate FCR activity. These unstable revertants, when again fully tumorigenic, completely lost FCR activity.

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Citations

Nov 1, 1992·Cancer Metastasis Reviews·V Costantini, L R Zacharski
Nov 1, 1984·Experimental Cell Research·B Azzarone, A Macieira-Coelho
Mar 15, 1984·International Journal of Cancer. Journal International Du Cancer·L Daya-GrosjeanA Benedetto
Feb 15, 1983·International Journal of Cancer. Journal International Du Cancer·L CuratoloA Macieira-Coelho

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