Relationship between hepatitis C clinical testing site and linkage to care

Open Forum Infectious Diseases
Sabrina A AssoumouBenjamin P Linas

Abstract

The Centers for Disease Control and Prevention recommends one-time hepatitis C virus (HCV) testing of the population born between 1945 and 1965 with follow-up RNA testing for those with reactive serology. To increase the rate of diagnosis, testing may be considered in settings other than outpatient clinics (OC), such as inpatient wards (IP) or emergency department (ED). We used electronic medical records to create a retrospective cohort with reactive HCV serology between 2005 and 2010 at an urban safety net hospital. We determined factors associated with linkage to HCV care as measured by HCV RNA testing, and we evaluated the rate of linkage to care according to diagnosis location (OC, IP, or ED). Individuals, 37 828, were tested and 5885 (16%) were reactive. Seropositivity was similar across all sites. Of the 4466 patients who met inclusion criteria, 3400 (76%) were diagnosed in the OC, whereas 967 (22%) and 99 (2%) were tested in the IP and the ED, respectively. A total of 2135 (48%) underwent HCV RNA testing. Using multivariable regression modeling, the following factors were independently associated with HCV RNA testing: diagnosis in the OC (odds ratio [OR], 1.64; 95% confidence interval [CI], 1.42-1.90); age at diagnosis i...Continue Reading

References

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May 27, 2014·Journal of Health Care for the Poor and Underserved·Sabrina A AssoumouBenjamin P Linas

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Citations

Mar 11, 2015·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Viktor V ChirikovCharles D Howell
Nov 3, 2016·Liver International : Official Journal of the International Association for the Study of the Liver·Zobair M YounossiStuart C Gordon
Nov 26, 2018·Liver International : Official Journal of the International Association for the Study of the Liver·Andrea LombardiUNKNOWN ESCMID Study Group for Viral Hepatitis (ESGVH)
Apr 9, 2020·Liver International : Official Journal of the International Association for the Study of the Liver·Andrew B MendlowitzMurray Krahn
Jan 13, 2018·European Journal of Gastroenterology & Hepatology·Anja LüllauJohannes Wiegand
Jan 10, 2017·Open Forum Infectious Diseases·Ricardo A FrancoJames W Galbraith
Oct 15, 2019·Journal of Clinical and Translational Hepatology·Sammy SaabGina Choi

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Methods Mentioned

BETA
Genotyping

Software Mentioned

STATA

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