Relationship between intelligence quotient (IQ) and cerebral metabolic rate of oxygen in patients with neurobehavioural disability after traumatic brain injury

Brain Injury : [BI]
Kagari AbikoKatsunori Ikoma

Abstract

Cerebral metabolism may play a significant role in neurobehavioural disability following traumatic brain injury (TBI). In this study, we examined the relationship between intelligence quotient (IQ) and the cerebral metabolic rate of oxygen (CMRO2) in the lateral prefrontal cortex, which was measured by 15O-labelled gas positron emission tomography (PET), in patients with TBI. The subjects were 12 patients (eight males and four females) who suffered from neurobehavioural disability following TBI. Their mean age was 33.3 years. The cause of injury was traffic accidents in all patients and the mean period after injury was 44.8 months. These patients underwent 15O-labelled gas PET and tests using either the Wechsler Adult Intelligence Scale-Revised (WAIS-R) or the Wechsler Intelligence Scale for Children-Revised (WISC-R). Pearson's correlation between CMRO2 and total IQ (TIQ) was calculated. A statistically significant correlation was observed between TIQ and CMRO2 in the right Brodmann areas (BAs) 44 and 45. The lower the WAIS score, the higher the CMRO2 in both areas. Neurological function negatively correlated with the metabolism of oxygen. It was possible that changes in brain networks increased the neuronal activity in the und...Continue Reading

References

Mar 1, 1986·The International Journal of Neuroscience·G J Larrabee
Nov 1, 1984·Journal of Clinical Neuropsychology·J D Matarazzo, D O Herman
Apr 1, 1982·Archives of Neurology·G FalziL A Vignolo
Jan 1, 1996·The Journal of Neuropsychiatry and Clinical Neurosciences·H GrossH Lavretsky
Dec 1, 1996·NeuroImage·K R PughJ C Gore
Aug 12, 1999·The Journal of Comparative Neurology·K AmuntsK Zilles
Jul 21, 2000·Science·J DuncanH Emslie
Feb 24, 2001·Proceedings of the National Academy of Sciences of the United States of America·M E RaichleG L Shulman
May 4, 2001·Brain : a Journal of Neurology·P C Fletcher, R N Henson
Jul 18, 2002·Journal of Neurology, Neurosurgery, and Psychiatry·B LevineD T Stuss
Nov 8, 2002·Archives of Physical Medicine and Rehabilitation·Eric M UmileRosette C Plotkin
Nov 30, 2002·Neuropsychologia·Charan RanganathMark D'Esposito
Feb 20, 2003·Nature Neuroscience·Jeremy R GrayTodd S Braver
Nov 15, 2003·Science·Etienne KoechlinFrédérique Kouneiher
Aug 26, 2004·Journal of the International Neuropsychological Society : JINS·William M PerlsteinRichard W Briggs
Oct 13, 2004·Applied Neuropsychology·Grant L IversonRussell L Adams
Jan 6, 2006·Neuropsychology Review·Juan M Muñoz-CespedesFernando Maestu
Mar 28, 2006·European Journal of Nuclear Medicine and Molecular Imaging·Tohru ShigaNagara Tamaki
Mar 21, 2007·NeuroImage·Randy L Buckner, Justin L Vincent
Jan 16, 2008·Physiological Reviews·Jun Tanji, Eiji Hoshi
Oct 22, 2008·Trends in Cognitive Sciences·Yosef Grodzinsky, Andrea Santi
Nov 18, 2008·Experimental Neurology·Robert F HuntBret N Smith
Jan 2, 2009·Neurorehabilitation and Neural Repair·Yun-Hee KimDuk L Na
Jan 22, 2009·Brain and Language·Simon S KellerNeil Roberts
Aug 19, 2010·Nuclear Medicine Communications·Frank Anthony ProvenzanoMasanori Ichise
Jan 25, 2011·Human Brain Mapping·Andrew R MayerRonald A Yeo
May 13, 2011·Neuropsychological Rehabilitation·Giovanni Berlucchi
Aug 16, 2011·Brain : a Journal of Neurology·David J SharpRobert Leech
Sep 22, 2011·Brain Injury : [BI]·Maki KasaharaEmmanuel A Stamatakis
Feb 4, 2012·Brain Structure & Function·Susanne J van VeluwSteven A Chance
Nov 24, 2012·Radiology·Yongxia ZhouYulin Ge
Jul 13, 2013·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Jon SkranesAnders M Dale
Jun 24, 2014·Journal of Neurotrauma·Umesh M VenkatesanFrank G Hillary
Aug 19, 2015·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Takehiro MinamotoNaoyuki Osaka

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Oct 2, 2019·Neurosurgical Focus·Jochem K H SpoorTjeerd H R de Jong
Oct 2, 2019·Neurosurgical Focus·Sophie FossJane E Schreiber
Apr 13, 2021·Work : a Journal of Prevention, Assessment, and Rehabilitation·Yuki IidaKatsunori Ikoma

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