PMID: 9438902Jan 24, 1998Paper

Relationship between lipid peroxidation and disease activity in patients with Behçet's disease

Journal of Dermatological Science
A OremB Vanizor

Abstract

Behçet's disease is a chronic multi-systemic disorder which is characterized by a relapsing systemic inflammatory process. The alteration of lipid profile and lipid peroxidation resulting from the inflammatory process may he associated with an increased risk for atherosclerosis in patients with Behcet's disease. We investigated lipids, lipoprotein and lipid peroxidation and their inter-relationships considering the disease activity. Eighteen patients (11 male and 7 female) and 20 age-matched healthy subjects (10 male and 10 female) were studied. Lipid profile including total cholesterol, triacylglycerol, HDL-cholesterol, LDL-cholesterol, lipoprotein(a), apoAI and apoB, and acute phase reactants including polymorphonuclear (PMN) elastase, PMN leukocyte count, erythrocyte sedimentation rate (ESR) and complements (C3, C4) were evaluated in patients in active and inactive periods of Behçet's disease and control subjects. The levels of thiobarbituric acid reactive substance (TBARS) were assessed as an indicator of lipid peroxidation. Lipid peroxidation was found to he increased in the active period compared to the inactive period of the disease and control subjects. Also, lipid peroxidation showed correlations of various degrees wit...Continue Reading

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Citations

Apr 2, 2004·Rheumatology International·Zeki YesilovaIsmail H Kocar
Dec 25, 2002·Clinical Biochemistry·Ibrahim Kökçam, Mustafa Naziroglu
Sep 21, 2004·The British Journal of Ophthalmology·S KarakucukM Ustdal
Jun 6, 2007·The Tohoku Journal of Experimental Medicine·Ahmet IsikSahabettin Selek
Sep 12, 2006·International Journal of Dermatology·Filiz CanpolatSelda Pelin Kartal Durmazlar
Jan 23, 2009·Journal of Cutaneous Pathology·Ali KaramanFatih Kara
Aug 16, 2002·The Tohoku Journal of Experimental Medicine·Kader KösePakize Doğan
Feb 15, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·C A M CaldasC R Gonçalves
Dec 1, 2004·International Journal of Dermatology·Umit TursenUgur Atik
May 24, 2007·The Journal of Dermatological Treatment·Basak KandiNevin Ilhan
Jul 5, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·A ÖremS Bahadir
Jul 2, 2003·Journal of the European Academy of Dermatology and Venereology : JEADV·A AkarA R Gur
Jun 22, 2005·Survey of Ophthalmology·Cem Evereklioglu

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