Relationship between metabolic syndrome and thyroid nodules in healthy Koreans

The Korean Journal of Internal Medicine
Juyoung ShinDong-Jun Lim

Abstract

This study evaluated the relationship between thyroid nodules and metabolic syndrome (MS) and its components in apparently healthy Koreans. We reviewed the records of 3,298 subjects with no noticeable symptoms who underwent thyroid ultrasound imaging as part of a routine check-up between July 2009 and June 2010; of these, 1,308 were excluded based upon predefined criteria. Among the remaining 1,990 patients, we examined the association between MS and its components and the incidence of thyroid nodules. Of the 1,990 subjects included in this study, 38.4% (n = 764) had thyroid nodules and 12.7% (n = 253) had MS. Female sex, older age, higher body mass index, larger waist circumference, higher glycated hemoglobin level, lower thyroid stimulating hormone level, and presence of MS were all closely related with the presence of thyroid nodules (all p < 0.05). Furthermore, the relevant number of MS components showed a positive linear correlation with the occurrence of thyroid nodules (p < 0.001). Evidence of MS alone was not independently associated with thyroid nodules after adjusting for sex and age in a multivariate binary logistic regression analysis; however, glycated hemoglobin for females and waist circumference for males, as we...Continue Reading

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Citations

Apr 9, 2017·Endocrine·Grigorios PanagiotouKalliopi Pazaitou-Panayiotou
Apr 11, 2017·Thyroid : Official Journal of the American Thyroid Association·Min-Hee KimMoo-Il Kang
May 4, 2018·International Journal of Endocrinology·Yi ChenYingli Lu
Jul 1, 2020·Metabolic Syndrome and Related Disorders·Qingrong PanGuang Wang
Jun 12, 2020·Thyroid : Official Journal of the American Thyroid Association·Joo-Hyun ParkYong-Gyu Park
Jun 15, 2021·Frontiers in Endocrinology·Yunhai LiGuosheng Ren
Oct 5, 2021·Frontiers in Endocrinology·Chenyu ZhangZhongyan Shan

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