Relationship between myelin sheath diameter and internodal length in axons of the anterior medullary velum of the adult rat

Journal of the Neurological Sciences
M IbrahimM Berry

Abstract

Relations between myelin sheath diameters and internodal lengths were measured in whole mounts of osmium stained intact anterior medullary velum (AMV) from glutaraldehyde perfused adult rats. The AMV is a sheet of CNS tissue which roofs the IVth ventricle and contains fascicles of myelinated fibres which arise mainly from the nucleus of the IVth cranial nerve. These fibers displayed a broad range of myelin sheath external diameters and internodal lengths, from < 1-12 microns and 50-750 microns, respectively. Myelin sheath external diameter was a measurement of the axonal diameter plus the thickness of its myelin sheath, while internodal length was measured as the distance between consecutive nodes. There was a broadly linear relationship between myelin sheath diameters and internodal lengths, with the smaller diameter sheaths tending to have shorter internodes than the larger. However, the correlation was weak and for any given diameter myelin sheaths displayed considerable variation in their internodal lengths. The smallest diameter myelin sheaths, < 4 microns, consistently had shorter internodes than predicted by a linear regression and, in an analysis of consecutive internodes in single fibres, the slope was flattened in fib...Continue Reading

References

Jan 1, 1975·Acta Neuropathologica·I R Griffiths, I D Duncan
Feb 1, 1981·Journal of the Neurological Sciences·W F Blakemore, J A Murray
Aug 1, 1982·Journal of the Neurological Sciences·K J SmithR C Patterson
May 1, 1981·Journal of the Neurological Sciences·R L FriedeM Diem
Feb 1, 1980·Journal of the Neurological Sciences·J A Murray, W F Blakemore
Dec 1, 1980·Journal of the Neurological Sciences·R L Friede, R Bischhausen
Dec 1, 1993·The Journal of Comparative Neurology·A M Butt, B R Ransom
Mar 1, 1993·Progress in Neurobiology·C HildebrandC Bjartmar
Nov 20, 1952·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·A HESS, J Z YOUNG
Jun 1, 1951·The Journal of Comparative Neurology·D BODIAN

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Citations

Dec 1, 1995·Journal of Neurocytology·M BerryA M Butt
Dec 25, 2009·Journal of the Association for Research in Otolaryngology : JARO·Jihwan WooPaul J Abbas
May 15, 2013·Computers in Biology and Medicine·Hamidreza Namazi, Vladimir V Kulish
Nov 1, 2008·Neuron Glia Biology·Alexander Gow, Jerome Devaux
Sep 20, 2011·Brain : a Journal of Neurology·Michelle A FarrarMatthew C Kiernan
Dec 18, 2013·Biomechanics and Modeling in Mechanobiology·Antoine JérusalemJosé M Peña
Jan 27, 1998·Experimental Eye Research·T FitzGibbon, Z Nestorovski
Sep 1, 2015·Current Biology : CB·Marie E BechlerCharles Ffrench-Constant
Aug 19, 2008·Progress in Histochemistry and Cytochemistry·Iris KulbatskiCharles H Tator
Jan 9, 2007·Current Biology : CB·D K Hartline, D R Colman
Nov 8, 2016·Scientific Reports·Sourabh KumarChristoph Simon
Oct 18, 2019·PLoS Computational Biology·Helmut Schmidt, Thomas R Knösche
Aug 24, 2017·Developmental Neurobiology·Marie E BechlerCharles Ffrench-Constant
Mar 8, 2019·International Journal of Molecular Sciences·Charles NicaiseJacques Gilloteaux
Sep 20, 2017·Developmental Neurobiology·Bethany R Kondiles, Philip J Horner
May 11, 2017·Experimental Brain Research·Giorgio M Innocenti
May 10, 2018·Sleep·Michele BellesiChiara Cirelli
Feb 23, 2018·The Tohoku Journal of Experimental Medicine·Tetsuya Akaishi
Mar 9, 2019·Neurochemical Research·Tanya L Brown, Wendy B Macklin
Jun 10, 2021·PLoS Computational Biology·Anamika Agrawal, Elena F Koslover

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