Relationship between N-terminal B-type natriuretic propeptide and right ventricular performance assessed by tissue Doppler imaging and speckle tracking echocardiography in children after surgical repair of tetralogy of Fallot

Kardiologia polska
Radosław Pietrzak, Bożena Werner

Abstract

The relationship between plasma levels of N-terminal B-type natriuretic propeptide (NT-proBNP) and parameters of right ventricular (RV) function was evaluated in patients after surgical repair of tetralogy of Fallot (ToF). 52 children comprised the study group (SG). The control group (CG) included 32 healthy children. Patient histories, measured NT-proBNP levels and transthoracic echocardiography parameters were analysed. Tissue Doppler imaging (TDI) demonstrated significant differences (p < 0.01) between SG and CG in regard to the following systolic and diastolic function parameters: peak systolic myocardial velocity (S', 5.9 ± 1.6 cm/s vs. 9.8 ± 2.3 cm/s), peak early diastolic velocity (E', 6.6 ± 2.9 cm/s vs. 11.6 ± 3.1 cm/s), and peak atrial diastolic velocity (A', 3.8 ± 1.6 cm/s vs. 6.6 ± 2.8 cm/s). Mean values of peak longitudinal strain (e) were significantly higher (p < 0.01) in SG compared to CG, including basal lateral segment (BL, -32.8 ± 12.1% vs. -51.5 ± 15.5%), medial lateral segment (ML, -23.8 ± 9.5% vs. -40.4 ± 14.9%), and apical lateral segment (AL, -16.9 ± 7.5% vs. -35.8 ± 13.43%). Mean plasma NT-proBNP level also differed significantly (p < 0.01) between SG and CG (286.0 ± 269.2 pg/mL vs. 153.1 ± 170.5 pg/mL, ...Continue Reading

Citations

Nov 20, 2016·Journal of Clinical Ultrasound : JCU·Ana Maria DarabanGheorghe Andrei Dan

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