Relationship Between Optical Coherence Tomography Angiography Peripapillary Vessel Density and Lamina Cribrosa Depth

Journal of Glaucoma
Kyu Sang EahKyung Rim Sung

Abstract

PRéCIS:: Peripapillary vessel density (pVD) assessed by optical coherence tomography angiography (OCT-A) has poor global and regional correlations with lamina cribrosa depth (LCD), except for the inferotemporal area. To investigate the global and regional relationship between the pVD assessed by OCT-A and LCD assessed by enhanced depth imaging spectral-domain optical coherence tomography (SD-OCT). A total of 38 eyes of 38 healthy subjects and 38 eyes of 38 glaucoma patients were included. Peripapillary microvasculature and lamina cribrosa were imaged by OCT-A and enhanced depth imaging SD-OCT, respectively. The pVD and LCD were measured at temporal, superotemporal, superonasal, nasal, inferonasal, and inferotemporal sectors. Global and regional correlations between pVD and LCD were evaluated in all subjects. The pVD (59.0±2.6 vs. 54.4±5.4%) and LCD (318.5±76.4 vs. 404.6±92.5 μm) were significantly different between healthy and glaucoma subjects. The average pVD assessed by OCT-A was not significantly correlated with average LCD assessed by SD-OCT (r=-0.160, P=0.167). Regional correlation between pVD and LCD was statistically significant only in the inferotemporal sector (r=-0.301 and P=0.008). In the linear regression analysis,...Continue Reading

References

Apr 1, 1981·Archives of Ophthalmology·H A QuigleyA E Maumenee
May 1, 1983·American Journal of Ophthalmology·H A QuigleyW R Green
Mar 1, 1981·Archives of Ophthalmology·R L Radius
Aug 2, 2002·Progress in Retinal and Eye Research·Josef FlammerEinar Stefánsson
Feb 17, 2009·Experimental Eye Research·Ian A Sigal, C Ross Ethier
Mar 29, 2014·Investigative Ophthalmology & Visual Science·Eun Ji LeeRobert N Weinreb
May 16, 2014·JAMA : the Journal of the American Medical Association·Robert N WeinrebFelipe A Medeiros
Feb 28, 2015·Investigative Ophthalmology & Visual Science·Sung Chul ParkRobert Ritch
Nov 3, 2015·Acta Ophthalmologica·Young Kook Kim, Ki Ho Park
Mar 5, 2016·Investigative Ophthalmology & Visual Science·Young Kook KimKi Ho Park
Jul 15, 2016·Investigative Ophthalmology & Visual Science·Adeleh YarmohammadiRobert N Weinreb
Sep 4, 2016·American Journal of Ophthalmology·Harsha L RaoCarroll A B Webers
Nov 17, 2016·Investigative Ophthalmology & Visual Science·Eun Ji LeeTae-Woo Kim
Apr 22, 2017·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Joong Won ShinMincheol Seong
Apr 23, 2017·The British Journal of Ophthalmology·Joong Won ShinMichael S Kook
Nov 29, 2017·Investigative Ophthalmology & Visual Science·Joong Won ShinJi Yoon Song

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Methods Mentioned

BETA
imaging technique

Software Mentioned

SPSS
AngioVue OCT - A
OCT
MATLAB

Related Concepts

Related Feeds

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.