Relationship between penile erection and the ratio of estradiol to testosterone: A retrospective study.

Andrologia
Dong PanSheng-Tian Zhao

Abstract

Previous studies have found that the ratio of estradiol to testosterone (E2/T ratio) has a negative effect on sexual function, but the relationship between the E2/T ratio and erection of the penis is not clarified. We conducted a retrospective study of 183 patients with erectile dysfunction and 52 healthy men to investigate the relationship between penis base erection and tip erection. All participants underwent nocturnal penile tumescence tests and medical history checks and had relevant biochemical and endocrine indicators measured. The ratio of estradiol to testosterone was calculated. The relationship between E2/T ratio and erectile time of penile tip and penile base was determined by univariate analysis, multivariate analysis and stratification analysis. After adjusting for mixed factors, the results showed that the E2/T ratio had a more significant negative effect on the base of the penis compared with the tip of the penis (Hazard ratio: -4.34 95% CI: -6.52, -2.16 p = .0001). Moreover, when the effective erection time was ≥10 min, the negative effect of E2/T on penile root erection was more obvious (HR ratio: -4.46 95% CI: -6.50, -2.43 p < .0001). In summary, our study demonstrated a negative relationship between E2/T rat...Continue Reading

References

Feb 1, 1988·Fertility and Sterility·R W Hudson
Jan 1, 1987·The Journal of Urology·G R FournierE A Tanagho
Dec 11, 1997·Nature·R A HessD B Lubahn
Apr 21, 2001·International Journal of Impotence Research·I G Motofei
May 2, 2003·Journal of Andrology·Abdulmaged M TraishIrwin Goldstein
Oct 17, 2003·International Journal of Impotence Research·J Buvat
Feb 20, 2004·International Journal of Impotence Research·O YamanK Anafarta
Apr 21, 2004·Circulation·Majon MullerYvonne T van der Schouw
May 18, 2004·Endocrine·George J Christ, Tom Lue
Feb 3, 2005·Asian Journal of Andrology·Vincenzo RochiraCesare Carani
Feb 25, 2005·International Journal of Impotence Research·C ForestaA Ferlin
Jul 12, 2005·The Journal of Urology·Allen D Seftel
Apr 21, 2006·The European Journal of Neuroscience·Masayoshi NomuraSonoko Ogawa
May 12, 2006·BJU International·José M Martínez-JabaloyasPascual Chuan-Nuez
Jul 3, 2007·Expert Opinion on Emerging Drugs·Stefan UckertUdo Jonas
Jul 22, 2008·Journal of Andrology·Aksam A Yassin, Farid Saad
Dec 4, 2008·The Journal of Clinical Endocrinology and Metabolism·Marcello MaggioLuigi Ferrucci
Jan 23, 2010·The Journal of Sexual Medicine·Dimitrios HatzichristouTara Symonds
Jan 23, 2010·The Journal of Sexual Medicine·Christian GratzkeChristian G Stief
Apr 15, 2010·The Journal of Sexual Medicine·Jacques BuvatMichael Zitzmann
Jan 29, 2014·BMJ : British Medical Journal·Asif MuneerManit Arya
Apr 8, 2014·Endocrine·Andrea SansoneAndrea Lenzi
Sep 23, 2014·The Journal of Sexual Medicine·Linda VignozziMario Maggi
Jan 13, 2016·The Journal of Sexual Medicine·Carlos LahozUNKNOWN SPREDIA-2 Group
Aug 18, 2017·Current Opinion in Urology·Paul J RizkMohit Khera
Dec 11, 2017·Advances in Experimental Medicine and Biology·Abdulmaged M Traish
Apr 30, 2019·Primary Care·Gretchen M Irwin

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Gastroenterology
H K Kley
Translational Andrology and Urology
Zhi-He XuSheng-Tian Zhao
Southern Medical Journal
R N Kampmeier
© 2022 Meta ULC. All rights reserved