PMID: 16618984Apr 19, 2006Paper

Relationship between plasma adiponectin levels and the metabolic syndrome among Korean people

Endocrine Journal
Seon Mee KimHye Soon Park

Abstract

We investigated the relationship between plasma adiponectin levels and the parameters of the metabolic syndrome among Koreans. In 67 male and 115 female subjects, aged from 30 to 70 years, plasma adiponectin levels were positively correlated with HDL-cholesterol levels (r = 0.295, P<0.001), but negatively correlated with waist circumference (r = -0.140, P = 0.020), triglycerides (r = -0.174, P = 0.021), fasting plasma glucose (r = -0.159, P = 0.036), fasting plasma insulin (r = -0.172, P = 0.023) and HOMA-IR (r = -0.182, P<0.001), after adjustment for age, sex, and BMI. Stepwise multiple regression analyses revealed that HDL-cholesterol, sex, and HOMA-IR were the independent associated factors for plasma adiponectin levels. Multiple logistic analyses demonstrated that HOMA-IR, BMI, and age were the predominant independent factors associated with the metabolic syndrome, while plasma adiponectin levels exhibited a protective effect against the presence of the metabolic syndrome according to both NCEP ATP III criteria and IDF definition. Hypoadiponectinemia is associated with the phenotype of the metabolic syndrome as well as components of the metabolic syndrome.

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Citations

Nov 25, 2011·BMC Medical Research Methodology·Anwar BoraiGordon Ferns
Aug 21, 2010·Journal of Atherosclerosis and Thrombosis·Ryuichi KawamotoNobuyuki Ohtsuka
Oct 3, 2009·Metabolism: Clinical and Experimental·Sang-Back KohJoshua Sung H You
Oct 23, 2008·Metabolism: Clinical and Experimental·Irina KowalskaMaria Gorska
Jun 7, 2007·Clinica Chimica Acta; International Journal of Clinical Chemistry·Christoph H SaelyHeinz Drexel
Oct 31, 2008·The Journal of Obstetrics and Gynaecology Research·Julie Bienertová-VaskůVít Unzeitig
Feb 14, 2009·Diabetes/metabolism Research and Reviews·Ji Eun YunKap Bum Huh
Jan 24, 2009·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Hyun Tae ParkSun Haeng Kim
Mar 29, 2014·International Journal of Nursing Practice·Chun-Ja KimSe-Won Kang
Jul 4, 2020·Journal of the Endocrine Society·Norimitsu MuraiShoichiro Nagasaka

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