PMID: 6133299Jan 1, 1983

Relationship between plasma concentration and arousal in normal subjects after single oral and parenteral doses of melperone, a butyrophenone neuroleptic

L Molander, L Borgström


The relationship between plasma concentration and effect on arousal was studied in normal subjects after single oral and parenteral doses of melperone. A strong correlation between plasma concentration and effect was found when the effector compartment and central compartment were in equilibrium. The relationship was independent of the route of administration.


Aug 7, 1978·Life Sciences·G SedvallB Wode-Helgodt
Dec 14, 1978·Archiv für Psychiatrie und Nervenkrankheiten·L BjerkenstedtG Sedvall
Oct 1, 1976·European Journal of Pharmacology·N Andén, M Grabowska
Dec 28, 1977·Archiv für Psychiatrie und Nervenkrankheiten·L BjerkenstedtG Sedvall
Jan 1, 1972·Psychopharmacologia·J Silverman
Jan 1, 1982·European Journal of Clinical Pharmacology·L BorgströmL Molander
Aug 1, 1981·The American Journal of Psychiatry·D E SternbergW E Bunney
Jan 18, 1980·Science·C R LakeW E Bunney


Mar 1, 1986·British Medical Journal·J Powell-TuckR A Parkins

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