PMID: 6133299Jan 1, 1983

Relationship between plasma concentration and arousal in normal subjects after single oral and parenteral doses of melperone, a butyrophenone neuroleptic

Psychopharmacology
L Molander, L Borgström

Abstract

The relationship between plasma concentration and effect on arousal was studied in normal subjects after single oral and parenteral doses of melperone. A strong correlation between plasma concentration and effect was found when the effector compartment and central compartment were in equilibrium. The relationship was independent of the route of administration.

References

Aug 7, 1978·Life Sciences·G SedvallB Wode-Helgodt
Dec 14, 1978·Archiv für Psychiatrie und Nervenkrankheiten·L BjerkenstedtG Sedvall
Oct 1, 1976·European Journal of Pharmacology·N Andén, M Grabowska
Dec 28, 1977·Archiv für Psychiatrie und Nervenkrankheiten·L BjerkenstedtG Sedvall
Jan 1, 1972·Psychopharmacologia·J Silverman
Jan 1, 1982·European Journal of Clinical Pharmacology·L BorgströmL Molander
Aug 1, 1981·The American Journal of Psychiatry·D E SternbergW E Bunney
Jan 18, 1980·Science·C R LakeW E Bunney

Citations

Mar 1, 1986·British Medical Journal·J Powell-TuckR A Parkins

Related Concepts

Melperon von ct
Vigilance, Cortical
Diastolic Blood Pressure
Butyrophenones
Electrocardiographic Recorders
Flicker Fusion
Hemodynamics
Sedatives
Injectables
Antipsychotic Effect

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