Relationship between poor decision-making process and fatigue perception in Parkinson's disease patients

Journal of the Neurological Sciences
Naia Sáez-FrancàsMiguel Casas

Abstract

Fatigue is a common non-motor symptom in Parkinson's disease patients. The reasons for its perception are not completely understood. One suggested possibility might be that perceived fatigue is related with abnormal interpretation of somatic symptoms. It has been described that somatic markers misinterpretation leads to poor decision-making. We hypothesized that fatigued Parkinson's disease patients would show poorer performance than non-fatigued in a decision-making task. To test our hypothesis, 89 Parkinson's disease patients were assessed for the presence of fatigue using the Parkinson Fatigue Scale. All patients were also administered scales evaluating psychopathology and neuropsychological tests, including the Iowa Gambling Task. 33 (37.1%) patients fulfilled the established criteria for fatigue. In the univariate analysis, fatigued patients showed higher levels of anxiety (state: p = 0.001, trait: p < 0.001), impulsivity (p = 0.051), and depression (p < 0.001) than non-fatigued patients. No statistically significant differences in other neuropsychological test results (Stroop, Trail Making Test, Tower of London) were found between fatigued and non-fatigued patients except for the Iowa Gambling Task, in which fatigued pati...Continue Reading

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Citations

Apr 19, 2015·Journal of Neurology, Neurosurgery, and Psychiatry·A KuppuswamyN S Ward
Jun 10, 2015·The Spanish Journal of Psychology·Sandra Fuentes-MárquezMiguel A Carrasco
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Jul 1, 2020·Journal of Neural Transmission·Mattia SicilianoAlessandro Tessitore
Mar 11, 2016·Movement Disorders Clinical Practice·Vladimir S KostićMilica Ječmenica-Lukić
Sep 19, 2017·The International Journal of Neuroscience·Li ZhangKezhong Zhang

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