Relationship between pre-TIPS liver perfusion by the portal vein and the incidence of post-TIPS chronic hepatic encephalopathy

The American Journal of Gastroenterology
Z HassounG Pomier-Layrargues

Abstract

In the present study we evaluated the predictive value of pretransjugular intrahepatic portosystemic shunt (TIPS) portal perfusion as assessed by Doppler ultrasonography for the onset of chronic encephalopathy after TIPS. A total of 231 cirrhotic patients were followed-up prospectively after TIPS placement. The pattern of intrahepatic portal flow was assessed before TIPS. Patients were divided into two groups according to Doppler findings. Group 1 comprised patients with prograde portal flow (n = 200), whereas group 2 comprised those with loss of portal perfusion (hepatofugal or back-and-forth flow or portal vein thrombosis; n = 31). The presence of chronic encephalopathy during a median follow-up of 32 months was prospectively recorded. The prognostic value of the following parameters for the onset of chronic recurrent encephalopathy after TIPS was evaluated: age, presence of encephalopathy before TIPS, alcoholism, Pugh score, and loss of portal perfusion before TIPS. The independent prognostic value of each variable was tested with a multiple logistic regression analysis. The two groups were comparable in terms of age, incidence of prior episodes of hepatic encephalopathy, and portacaval gradient before and after the procedur...Continue Reading

References

Nov 1, 1988·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·G Pomier-LayrarguesP Lavoie
Dec 1, 1996·Gastroenterology·P S Kamath, M A McKusick
Aug 1, 1996·Seminars in Liver Disease·R F Butterworth
Aug 1, 1996·Seminars in Liver Disease·G Pomier-Layrargues
Dec 11, 1997·AJR. American Journal of Roentgenology·D A ZuckermanC F Hildebolt

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Citations

Aug 14, 2012·International Journal of Hepatology·Gilles Pomier-LayrarguesPierre Perreault
Apr 21, 2004·European Journal of Gastroenterology & Hepatology·Ziad Hassoun, Gilles Pomier-Layrargues
Jul 5, 2006·Nature Clinical Practice. Gastroenterology & Hepatology·Guadalupe Garcia-Tsao
Jan 18, 2003·Current Gastroenterology Reports·Timothy M McCashland
Mar 24, 2010·European Journal of Gastroenterology & Hepatology·Jean-Marc PerarnauJean Ayoub
Jan 18, 2006·Digestive Diseases and Sciences·David C WolfGrigory Rozenblit
Apr 24, 2009·Liver International : Official Journal of the International Association for the Study of the Liver·Lei ChenRongquan Wang
May 15, 2010·Cardiovascular and Interventional Radiology·Ramakrishnan ArulrajDhiraj Tripathi
Apr 24, 2014·Clinical and Molecular Hepatology·Won Hyeok Choe
Mar 19, 2016·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Julien BissonnetteAurélie Plessier
Sep 26, 2015·Metabolic Brain Disease·Hui Juan ChenLong Jiang Zhang
May 22, 2020·Cardiovascular and Interventional Radiology·Wendy Melissa CoronadoBaljendra Kapoor

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