PMID: 8594634Jan 1, 1995Paper

Relationship between premacular cortical vitreous defects and idiopathic premacular fibrosis

Retina
T HikichiC L Schepens

Abstract

To investigate the relationship between the defect in the premacular cortical vitreous detached from the retina and the development of idiopathic premacular fibrosis. One hundred six consecutive patients (106 eyes) with posterior vitreous detachment but no other ocular disorders were prospectively studied. All follow-up periods were longer than 6 months. The vitreous condition was studied using an aspherical, +58.6-diopter preset lens with a slit-lamp. The detached premacular cortical vitreous was a continuous, unbroken sheet in 93 (88%) of the 106 eyes; in 13 (12%) eyes, the detached premacular cortical vitreous had an oval or round defect ranging from 4 to 7 disc diameters over the macula. At the study's conclusion, 36 (34%) of the 106 eyes had idiopathic premacular fibrosis; 70 (66%) eyes did not. The defect in the detached premacular vitreous was observed in 9 (25%) of the 36 eyes that eventually developed idiopathic premacular fibrosis and in 4 (6%) of the 70 eyes that did not undergo such development. The incidence of the defect in the detached premacular cortical vitreous was significantly higher in eyes with idiopathic premacular fibrosis than in eyes without (P = 0.011). Nine (69%) of thirteen eyes with the defect in t...Continue Reading

Citations

Jan 15, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Toshifumi YamashitaTaiji Sakamoto
Dec 11, 2013·Mediators of Inflammation·Malav JoshiJohn Byron Christoforidis
Apr 2, 2014·Mediators of Inflammation·Dorota RaczyńskaBartosz L Sikorski
Feb 23, 2010·American Journal of Ophthalmology·Mark W Johnson
Oct 2, 2015·Journal of Ophthalmology·Francesco SemeraroCiro Costagliola

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