Relationship Between Pulmonary Vein Reconnection and Atrial Fibrillation Recurrence: A Systematic Review and Meta-Analysis

JACC. Clinical Electrophysiology
Pablo B NeryDavid H Birnie

Abstract

This study systematically reviewed the prevalence of pulmonary vein (PV) reconnection in subjects with and without AF recurrence and assessed the relationship between PV reconnection and freedom from atrial fibrillation (AF). Pulmonary vein reconnection is frequently observed in patients experiencing recurrent AF post catheter ablation. However, its prevalence in AF-free patients has not been well studied. An electronic search was performed for studies describing PV electrical conduction in subjects with and without AF recurrence post PV isolation (PVI). Eleven of 5,665 articles met selection criteria. A total of 683 subjects were included in the meta-analysis; 379 had AF recurrence, and 304 were AF-free. Among patients with AF recurrence, 324 of 379 patients (85.5%) had at least 1 pulmonary vein reconnected. Among AF-free patients, 178 of 304 patients (58.6%) had at least 1 PV electrically reconnected, and 126 of 304 (41.4%) had durable PVI. The relative risk (RR) of recurrent AF was significantly lower with durable PVI than with PV reconnection (RR: 0.57; 95% confidence interval [CI]: 0.37 to 0.86; p = 0.008). Analysis of 7 studies including exclusively paroxysmal AF patients (n = 470) showed RR of 0.69 (95% CI: 0.45 to 1.05;...Continue Reading

References

Sep 3, 1998·The New England Journal of Medicine·M HaïssaguerreJ Clémenty
Mar 29, 2006·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Robert LemeryMichael Gollob
Feb 5, 2008·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Sanjay DixitFrancis E Marchlinski
Jul 1, 2009·Journal of Cardiovascular Electrophysiology·Sunny S PoWarren M Jackman
Feb 23, 2010·International Journal of Surgery·David MoherUNKNOWN PRISMA Group
May 28, 2010·Circulation. Arrhythmia and Electrophysiology·Srinivas R DukkipatiVivek Y Reddy
Jun 16, 2010·Pacing and Clinical Electrophysiology : PACE·Evgeny PokushalovDemosthenes G Katritsis
Feb 2, 2012·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Srinivas R DukkipatiVivek Y Reddy
Apr 28, 2012·Journal of Cardiovascular Electrophysiology·Sanjiv M NarayanWouter-Jan Rappel
Mar 19, 2013·Journal of the American College of Cardiology·Douglas L PackerUNKNOWN STOP AF Cryoablation Investigators
Aug 27, 2013·Journal of the American College of Cardiology·Demosthenes G KatritsisJohn P A Ioannidis
Oct 25, 2013·Journal of Cardiovascular Electrophysiology·Thomas J McGarry, Sanjiv M Narayan
Feb 20, 2014·JAMA : the Journal of the American Medical Association·Carlos A MorilloUNKNOWN RAAFT-2 Investigators
Jul 17, 2014·Circulation·Michel HaissaguerreRemi Dubois
Dec 3, 2014·Cardiology Clinics·Omer Berenfeld, José Jalife

❮ Previous
Next ❯

Citations

Aug 26, 2018·Pacing and Clinical Electrophysiology : PACE·Albert J RogersSanjiv M Narayan
Aug 30, 2019·Arrhythmia & Electrophysiology Review·Nicolas JohnerDipen C Shah
Nov 23, 2016·Current Opinion in Cardiology·Pablo B NeryCalum J Redpath
May 6, 2020·Journal of Cardiovascular Electrophysiology·Giuseppe StabileFrancesco Solimene
Feb 29, 2020·Journal of Cardiovascular Electrophysiology·Christopher J Bradley, David E Haines
May 30, 2020·Journal of Cardiovascular Electrophysiology·Dai InagakiMasayasu Hiraoka
Aug 30, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Elena ArbeloMario Martins Oliveira
Mar 21, 2018·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Henry ChubbReza Razavi
Aug 20, 2019·Circulation. Arrhythmia and Electrophysiology·Franziska FochlerNassir F Marrouche
May 19, 2019·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Jayson R BamanRod S Passman
Aug 28, 2016·European Heart Journal·Paulus KirchhofUNKNOWN ESC Scientific Document Group
Nov 4, 2016·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Paulus KirchhofKatja Zeppenfeld
Sep 25, 2016·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Paulus KirchhofKatja Zeppenfeld
Aug 3, 2020·Journal of Cardiovascular Medicine·Varnavas VarnavasGian-Battista Chierchia
Jul 6, 2020·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Marcus WieczorekReinhard Hoeltgen
Sep 18, 2017·The International Journal of Cardiovascular Imaging·Teresa StrisciuglioTom De Potter
Apr 4, 2019·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Rajesh MalikTina D Hunter
May 19, 2019·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·So-Ryoung LeeSeil Oh
Feb 26, 2019·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Clemens Jilek, Waqas Ullah
Jan 13, 2021·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Isaac L GoldenthalAngelo B Biviano
Jan 22, 2021·Journal of Cardiovascular Electrophysiology·Felix BourierMélèze Hocini
Jan 10, 2021·Journal of Cardiovascular Electrophysiology·Belinda SandlerUNKNOWN other members of the Imperial College London, Cardiovascular Study Group/Consortium
Dec 29, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Michelle LyckeSébastien Knecht
Feb 28, 2021·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Nikolaos PapageorgiouAnthony W C Chow
Feb 17, 2021·Journal of Cardiovascular Electrophysiology·Shunsuke MiyauchiYukiko Nakano
Oct 17, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Levio QuintoLluís Mont
Mar 23, 2021·Journal of Cardiovascular Electrophysiology·Simon P HansomMouhannad M Sadek
May 8, 2021·Heart, Lung & Circulation·Thirakan RattanakositRajiv Mahajan
Mar 22, 2021·Cardiovascular Research·Jorge G QuintanillaDavid Filgueiras-Rama

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiac Conduction System

The cardiac conduction system is a specialized tract of myocardial cells responsible for maintaining normal cardiac rhythm. Discover the latest research on the cardiac conduction system here.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.