Relationship between renal hemodynamics and urinary type IV collagen in patients with essential hypertension

Clinical and Experimental Hypertension : CHE
Daijiro EnomotoJitsuo Higaki

Abstract

Urinary type IV collagen excretion (uT4C) in diabetic patients is higher than in normal subjects. In this study, we investigated the relationship between uT4C and renal hemodynamics in 42 patients with essential hypertension. The renal resistive index (RI) is calculated from blood flow velocities measured using pulsed-wave in interlobar arteries. There was a significant correlation between uT4C to creatinine ratio (uT4C/uCr) and age, hemoglobin A1c (HbA1c), and RI. A stepwise regression analysis showed that RI was independently associated with uT4C/uCr. These results indicated that uT4C may be a marker of renovascular stiffness due to glomerulosclerosis in patients with essential hypertension.

References

May 1, 1992·Diabetic Medicine : a Journal of the British Diabetic Association·Y HayashiZ Ota
Apr 1, 1991·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·G H MostbeckD Tscholakoff
May 1, 1984·Kidney International·P S AvasthiE R Greene
Mar 9, 1999·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·R PontremoliG Deferrari
Aug 5, 2000·Journal of Diabetes and Its Complications·N KotajimaI Kobayashi
Jul 4, 2001·Journal of Clinical Laboratory Analysis·Y TominoM J Kim
Dec 6, 2002·Journal of the American Society of Nephrology : JASN·Pietro C Zucchelli
Mar 13, 2003·Kidney International·Kunitoshi IsekiShuichi Takishita
Oct 29, 2003·Circulation·Mark J SarnakUNKNOWN American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology,
Mar 6, 2004·American Journal of Hypertension·Takafumi OkuraJitsuo Higaki
Sep 27, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Ryota IkeeSoichiro Miura
Oct 29, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Marie EvansC Michael Fored
Nov 8, 2007·JAMA : the Journal of the American Medical Association·Josef CoreshAndrew S Levey

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