Relationship between renal stone formation, mitral annular calcification and bone resorption markers.

Annals of Saudi Medicine
Ahmet CelikNecat Yilmaz

Abstract

Mitral annular calcification (MAC) is associated with osteoporosis and there is evidence of reduced bone mineral density (BMD) in patients with renal stone formation (RSF). Therefore, we designed this study to test if RSF was associated with MAC and if this association could be linked to bone resorption. Fifty-nine patients (mean age, 41.5 years) with RSF and 40 healthy subjects (mean age, 44.2 years) underwent screening for MAC and BMD, and measurements were taken of serum and urine electrolytes, parathyroid hormone, alkaline phosphatase and urine dypyridoline. MAC was diagnosed in 11 (18%) patients with RSF compared with 1 (2.5%) control (P=.01). Urine phosphorus, magnesium, sodium, potassium and chloride levels were lower (P<.001, P=.02, P<.001, P<.001 and P<.001, respectively), but serum alkaline phosphatase, calcium and potassium levels were higher (P=.008, P=.007 and P=.001, respectively) in patients with RSF versus those without RSF. None of these abnormalities were found in patients or subjects with MAC. Urine pyridoline levels were higher and T-scores were more negative (more osteopenic) in patients and subjects with MAC than in those without MAC (P=.01 and P=.004, respectively). In a multivariate analysis, only T-scor...Continue Reading

References

Nov 1, 1991·The Journal of Urology·L BorghiA Novarini
Sep 19, 2001·Current Opinion in Lipidology·Y Tintut, L L Demer
Jun 17, 2004·American Heart Journal·Vedat DavutogluMehmet Aksoy
Aug 4, 2005·Urological Research·A Trinchieri
Apr 3, 2007·The American Journal of Cardiology·Vedat Davutoglu, Ibrahim Sari

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Citations

Jun 13, 2016·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·P LucatoN Veronese
Aug 9, 2020·Clinical Interventions in Aging·Paolo CarraiCarla Caffarelli

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