Relationship between risk factors and QUS in a European Population: The OPUS study

Bone
Alison StewartDavid M Reid

Abstract

There are many risk factors associated with low bone mineral density. Quantitative ultrasound (QUS) is a generally accepted method for measurement of bone and has been shown to be strongly associated with future fracture risk. The Osteoporosis and Ultrasound Study (OPUS) is a multi-centre European wide study examining 5 different QUS scanners (4 calcaneal, 1 finger device). The aim of this paper was to examine the relationship between risk factors (as assessed by questionnaire) and QUS measurements. 449 younger women (aged 20 to 39 years) and 2283 older women (aged 55 to 79 years) were included in this analysis. As expected, those with a self-reported previous fracture had lower QUS measurements than those without (P < 0.001). However, no significant difference was seen between those reporting a maternal hip fracture and those who did not report such an event. Differences were found for smokers vs. non-smokers for SOS but not for BUA measurements. Weight was positively correlated with all BUA variables but only with some SOS variables. We determined which risk factors were most strongly associated with QUS measurements by using step-wise multiple regression. Models for each QUS measurement were calculated, and the R2 values ran...Continue Reading

References

Sep 29, 1990·BMJ : British Medical Journal·R W PorterS B Palmer
Jul 1, 1995·British Journal of Rheumatology·D J TorgersonD M Reid
Mar 1, 1995·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·D C BauerK Stone
Mar 23, 1995·The New England Journal of Medicine·S R CummingsT M Vogt
Jan 1, 1995·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·D HansP J Meunier
Feb 1, 1996·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·D J TorgersonD M Reid
Aug 1, 1997·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·S L GreenspanE S Orwoll
Nov 3, 1998·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·P ThompsonR Oliver
Dec 11, 1999·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·E W GreggJ A Cauley
Feb 9, 2000·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S ChengH K Genant
May 29, 2000·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J HuopioE Alhava
Jul 27, 2000·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·F E AlenfeldJ Braun
Oct 13, 2000·QJM : Monthly Journal of the Association of Physicians·A StewartD M Reid
Feb 24, 2001·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·M L FrostI Fogelman
Apr 11, 2001·Archives of Internal Medicine·J A BaronS Ljunghall
Jun 19, 2001·Annals of the Rheumatic Diseases·P RöbenC C Glüer
Dec 12, 2001·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·O ArdicogluI Pekkutucu
Apr 12, 2002·Journal of the American Geriatrics Society·Deborah M KadoUNKNOWN Study Of Osteoporotic Fractures Research Group
May 15, 2002·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Sun H LeeUNKNOWN EPIDOS Group. Epidemiologie de l'Osteoporose Study
Aug 20, 2002·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·E R BarrosM Lazaretti-Castro
May 6, 2003·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·G HaugebergT K Kvien
May 6, 2003·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·K M KnappI Fogelman
Apr 8, 2004·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Claus C GlüerSami Kolta
Aug 12, 2004·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·P BalikianD T Baran

❮ Previous
Next ❯

Citations

Nov 1, 2007·Der Radiologe·C Kasperk
Feb 22, 2012·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M A PaggiosiR Eastell
Sep 2, 2008·Journal of Orthopaedic Trauma·Cory CollingeLaura Gehrig
Dec 3, 2014·Ultrasound in Medicine & Biology·Francesco ConversanoSergio Casciaro
Dec 2, 2008·Best Practice & Research. Clinical Rheumatology·Glenn Haugeberg
Nov 26, 2008·Best Practice & Research. Clinical Endocrinology & Metabolism·James F Griffith, Harry K Genant
Apr 2, 2016·Ultrasound in Medicine & Biology·Sergio CasciaroFrancesco Conversano
Feb 19, 2015·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·E V McCloskeyH Johansson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
P AssantachaiK Sitthichai
Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
Claus C GlüerSami Kolta
Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
M L FrostI Fogelman
© 2022 Meta ULC. All rights reserved