Relationship Between Sarcopenia and Albuminuria: The 2011 Korea National Health and Nutrition Examination Survey

Medicine
Tae Nyun KimDong-Jun Kim

Abstract

Studies have shown that albuminuria, obesity, and sarcopenia may share pathophysiological processes related to cardiovascular disease risk. Their direct relationships, however, have not been examined. This study investigated the association between albuminuria and sarcopenia in a representative fraction of the Korean population.Of the 10,589 people who participated in the 2011 Korea National Health and Nutrition Examination Survey, 2158 participants aged over 19 years had been tested for albumin-to-creatinine ratio and for body composition data using dual-energy x-ray absorptiometry. Albuminuria was defined as an albumin-to-creatinine ratio ≥30 mg/g. Sarcopenia was defined as a skeletal muscle index (SMI) (SMI (%) = total appendicular skeletal muscle mass [kg]/weight [kg] × 100) of less than 1 standard deviation (SD) (grade 1) or 2 SD (grade 2) below the sex-specific mean for a younger reference group.The prevalence of albuminuria was higher in those with grade 2 sarcopenia than in those with a normal SMI or grade 1 sarcopenia (33.3% versus 8.4% and 8.9%; P < 0.001). Conversely, grade 2 sarcopenia was also more prevalent in participants with albuminuria than in those with the upper tertile of normoalbuminuria. In addition, mult...Continue Reading

References

Aug 1, 1990·The American Journal of Clinical Nutrition·S B HeymsfieldR N Pierson
Feb 1, 1996·The American Journal of Clinical Nutrition·S WelleG Forbes
Jun 1, 1996·The American Journal of Clinical Nutrition·Z M WangS B Heymsfield
Apr 23, 1999·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·W F Keane, G Eknoyan
Dec 12, 2001·Experimental Gerontology·H BruunsgaardB K Pedersen
May 27, 2003·Journal of Cellular Physiology·Erik J Henriksen, Stephan Jacob
Apr 13, 2004·International Journal of Epidemiology·Matthew F YuyunUNKNOWN European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population study
Jun 25, 2005·International Journal of Cardiology·E Erdmann
Jul 20, 2006·Gerontology·Deepa SumukadasMarion E T McMurdo
Aug 25, 2006·Nature Clinical Practice. Endocrinology & Metabolism·Per-Henrik GroopMerlin C Thomas
Apr 3, 2007·The American Journal of Medicine·Hideo SasakiShoichiro Fujita
Apr 26, 2007·Diabetes Care·Prataap K Chandie ShawTon J Rabelink
Aug 26, 2009·Women's Health·Laura J MillerRenu Gupta
Oct 28, 2011·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Caterina GuidoneGeltrude Mingrone
Nov 15, 2011·Pharmacology & Therapeutics·Noboru Toda
Jan 17, 2012·Diabetes & Metabolism Journal·Sang Woo Oh
Mar 3, 2012·Clinical Journal of the American Society of Nephrology : CJASN·Caitlin E CarterJoachim H Ix
Aug 21, 2012·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·K L Timmerman, E Volpi
Oct 11, 2012·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·S De CosmoV Trischitta
Dec 30, 2014·Journal of Cellular Biochemistry·Tae Nyun Kim, Kyung Mook Choi

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Citations

Apr 14, 2017·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Hye Soo ChungKyung Mook Choi
Oct 25, 2020·Journal of Nephrology·Boris ZingermanRuth Rahamimov
Sep 8, 2020·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Akinori HaraHiroyuki Nakamura
Nov 13, 2020·International Journal of Endocrinology·L M PechmannV Z C Borba
Jan 26, 2021·The Journal of Nutrition, Health & Aging·X YangY Li
Oct 17, 2021·Scientific Reports·Ming-Dian YuWen-Xin Chen
Nov 10, 2021·Clinical Science·Jeffrey KingsleySatoru Eguchi

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