PMID: 11324724Apr 28, 2001Paper

Relationship between severity of reflux esophagitis according to the Los Angeles classification and esophageal motility

Journal of Gastroenterology
T SugiuraM Kobayashi

Abstract

We investigated the relationship between the severity of reflux esophagitis (RE) according to the Los Angeles (LA) classification and esophageal motility. We examined 28 healthy subjects (HS) and 48 RE patients (grade A of the LA classification, 16 patients; grade B, 16 patients; grade C or D, 16 patients). Esophageal manometry was performed by the intraluminal microtransducer method. Resting lower esophageal sphincter (LES) pressure was assessed by the rapid pull-through method. Esophageal contraction after ten repeated 5-ml water swallowings separated by 30-s intervals was measured at 3, 8, 13, and 18 cm above the LES. The resting LES pressure and the amplitude of esophageal contraction 3 cm above the LES in the grades C + D group were significantly lower than those in the HS group. The amplitude of esophageal contraction 3 cm above the LES in the grade B group was significantly lower than those in the grade A group and the HS group. The frequency of failed peristalsis in the grades C + D group was significantly higher than that in the HS group and the grade A and grade B groups. The present findings suggested that the severity of RE according to the LA classification would be likely to mainly reflect esophageal volume cleara...Continue Reading

Citations

Jul 28, 2004·Gastrointestinal Endoscopy·Devjit S Nayar, Michael F Vaezi
Mar 21, 2002·Journal of Gastroenterology and Hepatology·K AdachiY Kinoshita
Oct 1, 2009·Journal of Gastroenterology and Hepatology·Shigeaki YasakaToshio Fujioka
Mar 20, 2008·World Journal of Gastroenterology : WJG·Wei LiZhong-Lin Yu
Oct 3, 2014·Digestive Diseases and Sciences·Prathima GuntipalliDon C Rockey
Oct 11, 2011·Journal of Gastroenterology·Kenji FurutaYoshikazu Kinoshita
Dec 1, 2009·Clinical Journal of Gastroenterology·Katsuhiko Iwakiri
Dec 4, 2010·Best Practice & Research. Clinical Gastroenterology·Sabine Roman, John E Pandolfino
Aug 24, 2005·The Journal of Surgical Research·Brant K OelschlagerCarlos A Pellegrini
Mar 7, 2015·Best Practice & Research. Clinical Gastroenterology·Sabine Roman, Peter J Kahrilas
Mar 8, 2018·Digestion·Mariko UmezawaKatsuhiko Iwakiri
Jul 20, 2010·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Samantha ScherbaumThorsten Burmester
Oct 24, 2006·International Journal of Clinical Oncology·Hitoshi Katai
Nov 5, 2019·Esophagus : Official Journal of the Japan Esophageal Society·Nana TakenouchiKatsuhiko Iwakiri
Jul 26, 2018·Journal of Medical Ultrasonics·Hiroki SuharaHidemi Goto
Aug 28, 2020·The Cochrane Database of Systematic Reviews·Shino KikuchiNorio Watanabe
Feb 17, 2021·Esophagus : Official Journal of the Japan Esophageal Society·Tomohide TanabeKatsuhiko Iwakiri
Apr 23, 2021·Esophagus : Official Journal of the Japan Esophageal Society·Mai KoedaKatsuhiko Iwakiri
Sep 19, 2021·Esophagus : Official Journal of the Japan Esophageal Society·Mai KoedaKatsuhiko Iwakiri

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