Relationship between sleep apnea syndrome and sleep blood pressure in patients without hypertension

Journal of cardiology
Hiromitsu SekizukaFumihiko Miyake

Abstract

Ambulatory blood pressure monitoring (ABPM) provides an accurate assessment of blood pressure (BP) and shows non-dipper BP pattern in many sleep apnea syndrome (SAS) patients with hypertension (HTN); however, little information is available on the relationship between the severity of SAS and circadian BP changes in SAS patients without HTN. This study investigated whether SAS patients without HTN would have different BP courses in the severity of SAS. Seventy-four consecutive outpatients without HTN [systolic BP (BPs) at clinic <140mmHg and/or diastolic BP (BPd) at clinic <90mmHg], who received no antihypertensives, underwent overnight polysomnography (PSG) and ABPM. The apnea-hypopnea index (AHI) was calculated from the PSG results; patients were stratified into the following 4 groups based on their AHI: non-SAS, mild-, moderate-, or severe-SAS. The diurnal BPs and BPd showed no differences in the severity of SAS; however, the sleep BPs, lowest BPs, and pre-awake BPs were significantly higher in the severe-SAS group than the non-SAS group (p=0.02, p=0.04, and p=0.006, respectively). The sleep BPd and pre-awake BPd were significantly higher in the severe-SAS than the non-SAS (p=0.01 and p=0.0003, respectively) and mild-SAS (p=0...Continue Reading

References

Oct 1, 1995·The Journal of Clinical Investigation·V K SomersF M Abboud
Nov 1, 1994·Diabetes Research and Clinical Practice·M IwaseM Fujishima
Dec 26, 2001·American Journal of Respiratory and Critical Care Medicine·R S Leung, T D Bradley
Mar 28, 2003·The New England Journal of Medicine·Yasuyuki KanekoT Douglas Bradley
Oct 14, 2003·Journal of Applied Physiology·Michael J CutlerMichael L Smith
Mar 25, 2005·The New England Journal of Medicine·Apoor S GamiVirend K Somers
Jun 29, 2005·Diabetes·Kamal RahmouniWilliam G Haynes
Mar 25, 2008·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Kohei NagataKenjiro Kimura
Aug 30, 2008·International Heart Journal·Kihei YoneyamaSatoshi Watanabe
Mar 6, 2009·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Hirofumi TomiyamaAkira Yamashina
Mar 24, 2009·Journal of cardiology·Yuki IshibashiSatoshi Watanabe

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Citations

Jan 18, 2014·Annals of the American Thoracic Society·Kimihiko MuraseKazuo Chin
Jul 3, 2015·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Hiroyuki KayanoYouichi Kobayashi
May 10, 2016·Clinical and Experimental Hypertension : CHE·Hiromitsu SekizukaYoshihiro J Akashi
Dec 3, 2016·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Hiromitsu SekizukaYoshihiro J Akashi
Jan 13, 2018·Internal Medicine·Hiromitsu SekizukaYoshihiro J Akashi
May 31, 2018·Journal of Hypertension·Takeshi MatsumotoUNKNOWN Nagahama study group
Oct 22, 2010·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Hiromitsu SekizukaFumihiko Miyake

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