Relationship between the atopy patch test and clinical expression of the disease in children with atopic eczema/dermatitis syndrome and respiratory symptoms

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
N FuianoGianni Bona

Abstract

The atopy patch test (APT) may be the only positive skin test result in patients with either atopic eczema/ dermatitis syndrome (AEDS) or respiratory abnormalities with or without AEDS. To investigate the possible significance of APT to dust mite by comparing the positive result to this test with that of the skin prick test (SPT) in patients with different characteristics. A total of 297 individuals (178 boys and 119 girls) aged 5 to 221 months (mean [SD] age, 64.5 [42.1] months; median age, 58 months) were included in this study. Participants were divided into 4 groups: current AEDS, current AEDS and respiratory symptoms, past AEDS and respiratory symptoms, and respiratory symptoms with neither current nor past AEDS (control group). All the patients underwent SPT and APT using house dust mite extract. In the study groups, the rate of positivity was significantly higher for APT, whereas in the control group, there were significantly more positive results to SPT (P < .001 for both). Multivariate analysis showed that there was a high probability of a positive APT result in patients with AEDS (odds ratio [OR], 17.4), with AEDS and respiratory disease (OR, 21.9), and with past AEDS and respiratory disease (OR, 22.8). These patients...Continue Reading

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Citations

May 18, 2011·International Archives of Allergy and Immunology·Larry G Arlian, Marjorie S Morgan
Jul 3, 2013·The World Allergy Organization Journal·Cristoforo IncorvaiaGiorgio W Canonica
Nov 19, 2010·Advances in Medical Sciences·B Cudowska, M Kaczmarski
May 8, 2014·Journal of Exposure Science & Environmental Epidemiology·Maya RamagopalStuart L Shalat
Apr 5, 2011·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Nicola Fuiano, Cristoforo Incorvaia
Mar 1, 2012·Allergology International : Official Journal of the Japanese Society of Allergology·Nicola Fuiano, Cristoforo Incorvaia
May 9, 2015·Clinical and Molecular Allergy : CMA·Nicola FuianoCristoforo Incorvaia C
Jun 23, 2016·Journal of the European Academy of Dermatology and Venereology : JEADV·X DouJ Zhang
Aug 9, 2011·Current Opinion in Allergy and Clinical Immunology·Heidi Olze, Torsten Zuberbier
Dec 7, 2013·São Paulo Medical Journal = Revista Paulista De Medicina·Raquel Prudente de Carvalho BaldaçaraMario Cesar Pires
Jun 28, 2018·Allergy, Asthma & Immunology Research·Aneta WagnerWaldemar Wagner

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