Relationship Between the Size of Metastatic Lymph Nodes and Positron Emission Tomographic/Computer Tomographic Findings in Patients with Esophageal Squamous Cell Carcinoma

World Journal of Surgery
Seong Yong ParkCheol Keun Park

Abstract

We measured the sizes of metastatic lymph nodes and the relationships thereof by (18)F-fluorodeoxyglucose positron emission tomography/computer tomography (PET/CT). We identified risk factors for nodal upstaging in patients with esophageal squamous cell carcinoma (ESCC). Eighty-five patients with ESCC who underwent esophagectomy with extensive mediastinal lymphadenectomy were assessed. Two radiologists blinded to pathology data reviewed PET/CT scans, evaluating both primary tumors and lymph node involvement. A pathologist examined all metastatic lymph nodes in terms of maximal diameter (LNmax), the size of the metastatic focus (Fmax), and the metastasis occupation ratio (MOR = Fmax/LNmax). The maximal tumor length averaged 2.9 ± 0.2 cm and the mean SUVmax of the primary lesion 5.3 ± 0.5. On PET/CT scans, 26 (30.6 %) patients exhibited nodal metastasis and 59 (69.4 %) did not. Pathology grades of pN0, pN1, pN2, and pN3 were assigned to 45 (52.9 %), 24 (28.2 %), 13 (15.3 %), and 3 (3.5 %) patients, respectively. Nodal upstaging was evident in 29 (34.1 %) cases. In 123 metastatic nodes of 4212 nodes dissected, the LNmax was 6.60 ± 0.39 mm, the Fmax 4.47 ± 0.35 mm, and the MOR 0.68 ± 0.03. Of 123 nodes, 85 (69.1 %) were retrieved f...Continue Reading

References

Apr 3, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·S B HoschJ R Izbicki
Apr 7, 2010·Annals of Surgical Oncology·Thomas W RiceValerie W Rusch
Nov 15, 2011·Australasian Physical & Engineering Sciences in Medicine·J CallahanT Kron

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Citations

Aug 18, 2017·Annals of Surgery·Bin Li, Haiquan Chen
Jul 10, 2018·Annals of Surgery·Bin Li, Haiquan Chen
Aug 5, 2017·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Jan-Christopher MetzgerArnulf Mayer
Jul 3, 2018·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·J ChenC Chen
Jun 25, 2017·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Seong Yong ParkKyung Young Chung

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