Relationship between transmural extent of necrosis and quantitative recovery of regional strains after revascularization

JACC. Cardiovascular Imaging
Bernhard L GerberJean-Louis J Vanoverschelde

Abstract

To better understand the quantitative relationship of recovery of regional and global dysfunction after revascularization in chronic infarcts with variable transmural extent of necrosis by delayed enhanced cardiac magnetic resonance. Studies relating transmurality of delayed enhanced magnetic resonance to functional recovery in dysfunctional myocardium using semiquantitative Likert scales have demonstrated the intermediate likelihood (50% probability) of recovery of dysfunction in subendocardial scars. Forty-two patients with chronic left ventricular dysfunction due to coronary artery disease underwent tagged and delayed enhanced magnetic resonance before and 10 +/- 7 months after revascularization (coronary artery bypass graft: 35, percutaneous transluminal coronary angioplasty: 7). Left ventricular ejection fraction and regional mid-myocardial Eulerian radial thickening strain (Err) and mid-myocardial, subendocardial, and subepicardial Eulerian circumferential shortening strain (Ecc) strains were quantified in 16 segments per patient before and after revascularization and related to pre-operatively measured transmurality of necrosis. At baseline, 256 of 672 segments were dysfunctional, having <2 SD (i.e., >-10%) mid-myocardia...Continue Reading

References

Sep 27, 2005·European Heart Journal·Osvaldo Pereztol-ValdésJordi Soler-Soler
Jun 3, 2008·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Bernhard L GerberJean-Louis J Vanoverschelde

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Citations

Apr 1, 2011·Journal of Cardiovascular Translational Research·Moriel H Vandsburger, Frederick H Epstein
Dec 18, 2010·European Heart Journal·Frank A FlachskampfWerner G Daniel
Aug 15, 2014·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Xavier FreixaAnita W Asgar
Jan 21, 2012·Journal of the American College of Cardiology·Andreas SchusterEike Nagel
Mar 1, 2012·Journal of the American College of Cardiology·Katherine C Wu
Jul 17, 2010·JACC. Cardiovascular Imaging·Eike Nagel, Andreas Schuster
Apr 5, 2014·Cardiology in Review·Roman PanovskyVladimir Kincl
Jun 8, 2021·European Heart Journal Cardiovascular Imaging·Ana G AlmeidaUNKNOWN 2018–2020 EACVI President:

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