Relationship between urinary 15-F2t-isoprostane and 8-oxodeoxyguanosine levels and breast cancer risk.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
Pavel RossnerRegina M Santella

Abstract

To evaluate the role of oxidative stress in breast cancer, we measured urinary levels of 15-F(2t)-isoprostane (15-F(2t)-IsoP) and 8-oxodeoxyguanosine (8-oxodG) in 400 cases and 401 controls, participants of the Long Island Breast Cancer Study Project. We also analyzed the effect of different factors that are associated with oxidative stress and might influence 15-F(2t)-IsoP and 8-oxodG levels. We observed a statistically significant trend in breast cancer risk with increasing quartiles of 15-F(2t)-IsoP levels [odds ratio (OR), 1.25; 95% confidence interval (95% CI), 0.81-1.94; OR, 1.53; 95% CI, 0.99-2.35; OR, 1.88; 95% CI, 1.23-2.88, for the 2nd, 3rd, and 4th quartile relative to the lowest quartile, respectively; P(trend) = 0.002]. Although it is possible that increased levels may reflect the stress associated with recent treatment, the positive association was also observed when the analyses were restricted to case women for whom chemotherapy and radiation therapy had not yet been initiated at the time of the urine collection. The association with the highest quartile compared with lowest quartile of 15-F(2t)-IsoP was similar across strata of age, physical activity, fruit and vegetable intake, alcohol intake, cigarette smokin...Continue Reading

References

Nov 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·J D MorrowL J Roberts
Jul 1, 1996·Circulation·M ReillyG A FitzGerald
May 9, 1998·Proceedings of the National Academy of Sciences of the United States of America·D PraticòG A FitzGerald
Sep 24, 1999·The Journal of Clinical Investigation·E A MeagherG A FitzGerald
Feb 3, 2000·Free Radical Biology & Medicine·M LodoviciP Dolara
Mar 11, 2000·Free Radical Research·S PourcelotA Favier
May 19, 2000·Breast Cancer Research and Treatment·G RayS A Husain
Oct 26, 2000·Journal of Chromatography. B, Biomedical Sciences and Applications·T ObataT Kawamoto
Feb 24, 2001·Antioxidants & Redox Signaling·C B Ambrosone
May 15, 2001·Journal of Clinical Pharmacy and Therapeutics·A GönençB Simşek
Jun 28, 2001·Prostaglandins, Leukotrienes, and Essential Fatty Acids·F ChehneH Sinzinger
Oct 16, 2002·Trends in Pharmacological Sciences·Jean-Luc CracowskiGermain Bessard
Nov 27, 2002·Journal of the American Dietetic Association·R J StewartR L Prior
Mar 5, 2003·Arteriosclerosis, Thrombosis, and Vascular Biology·John F KeaneyUNKNOWN Framingham Study
Jul 18, 2003·Clinica Chimica Acta; International Journal of Clinical Chemistry·Chiuan Chian ChiouJames T Wu
Oct 30, 2003·Free Radical Biology & Medicine·Masaru NakanoIkuhiro Yamasawa
Dec 23, 2003·Clinica Chimica Acta; International Journal of Clinical Chemistry·Lily L WuJames T Wu
Jan 28, 2004·Annual Review of Pharmacology and Toxicology·James E Klaunig, Lisa M Kamendulis
Mar 17, 2004·The Journal of Urology·Hideaki MiyakeHiroshi Eto
Jun 19, 2004·International Journal of Environmental Health Research·Amr S SolimanMelissa L Bondy
Aug 25, 2004·Environmental Research·Marilie D GammonRegina M Santella
Mar 15, 2005·Free Radical Research·Siamak HaghdoostMats Harms-Ringdahl
Apr 30, 2005·Nutrition and Cancer·Cynthia A ThomsonJohn P Pierce
May 26, 2005·Mutation Research·Marcus S CookeRyszard Olinski
Oct 19, 2005·Annals of Epidemiology·Mary Beth TerryMarilie D Gammon

❮ Previous
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Citations

Mar 29, 2012·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Christelle MachonJean-Paul Cristol
Sep 21, 2013·Breast Cancer Research and Treatment·Renée T FortnerA Heather Eliassen
Sep 8, 2007·Cancer Causes & Control : CCC·Geoffrey C Kabat, Thomas E Rohan
Jul 4, 2012·Antioxidants & Redox Signaling·Samar BasuMarie-Paule Vasson
Aug 4, 2010·American Journal of Epidemiology·Enrique F SchistermanUNKNOWN BioCycle Study Group
Jul 16, 2010·Journal of Oncology·Thomas E RohanGeoffrey C Kabat
Jun 18, 2009·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Meira EppleinLoïc Le Marchand
Aug 9, 2013·Reproductive Biology and Endocrinology : RB&E·Umberto CornelliAnnarosa Finco
Apr 22, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Qi DaiWei Zheng
Jun 19, 2013·PloS One·Bharat ThyagarajanJian-Min Yuan
Nov 28, 2012·Contemporary Clinical Trials·Andrea Y ArikawaKathryn H Schmitz
Nov 1, 2011·Free Radical Research·Pavel Rossner, Radim J Sram
Dec 17, 2009·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Joanne L WattersJames A Swenberg
Jun 25, 2008·Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases·Hiroshi MitsumotoPam Factor-Litvak
Aug 14, 2012·Translational Research : the Journal of Laboratory and Clinical Medicine·Deepti PandeH D Khanna
Sep 29, 2011·Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie·F PetitpasV Prevost
Jun 26, 2010·Contemporary Clinical Trials·Andrea Y ArikawaKathryn H Schmitz
Nov 6, 2007·Journal of Cellular and Molecular Medicine·Pavel RossnerRegina M Santella
Feb 3, 2007·International Journal of Cancer. Journal International Du Cancer·Ferdinando MannelloEdward R Sauter
Dec 18, 2008·International Journal of Cancer. Journal International Du Cancer·Jing ShenRegina M Santella
Nov 14, 2012·Molecular Nutrition & Food Research·Elisabeth MüllnerKarl-Heinz Wagner
Oct 29, 2015·BioMed Research International·Betânia de Jesus E Silva de Almendra FreitasPatricia Moriel
Mar 22, 2014·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·K D CrewD L Hershman
Nov 15, 2012·Journal of Nutrition and Metabolism·Mo'ez Al-Islam Ezzat FarisMohammad Khalil Mohammad
Dec 3, 2014·Biochimica Et Biophysica Acta·Ginger L MilneL Jackson Roberts
Oct 22, 2016·The British Journal of Nutrition·Chelsea AndersonHazel B Nichols
Oct 27, 2016·International Journal of Cancer. Journal International Du Cancer·Patrizia FerroniFiorella Guadagni
Mar 17, 2012·British Journal of Clinical Pharmacology·Barry Halliwell
May 19, 2017·Epidemiology·Hazel B NicholsDale P Sandler

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