Relationship between velvet antler ossification and PTH and androgen serum levels in Tarim Red deer (Cervus elaphus)

Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology
Dayong TaoJifeng Jiao

Abstract

Ossification degree is one of the primary variables affecting the medicinal value of velvet antler. Multiple factors regulate the calcification of velvet antler. We studied the relationship between the ossification of velvet antlers and the serum levels of parathyroid hormone (PTH) and androgen (ADG) in Tarim red deer. Enzyme-linked immunosorbent assays (ELISA) and atomic absorption spectrometry demonstrated that the changes in serum PTH and ADG levels nearly paralleled antler ossification during Tarim red deer antler mineralization. These results suggest that regulating the levels of serum PTH and ADG could decrease the calcification rate of velvet antlers in Tarim red deer. We conclude that PTH might increase antler ossification via the cAMP signaling pathway, and ADG possesses the dual roles of promoting both antler ossification and growth in Tarim red deer. This study suggests that we might be able to artificially control antler ossification to improve its medical value via the PTH or/and ADG pathway. J. Exp. Zool. 323A: 696-703, 2015. © 2015 Wiley Periodicals, Inc.

References

Jan 1, 1992·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·J M Hock, I Gera
May 1, 1981·Journal of Reproduction and Fertility·A J Sempéré, J Boissin
Apr 1, 1995·Metabolism: Clinical and Experimental·O ArisakaK Yabuta
Jun 3, 1999·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·T T AndreassenH Oxlund
Dec 12, 2001·Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society·M SadighiJ M Suttie
Feb 24, 2005·Journal of Experimental Zoology. Part A, Comparative Experimental Biology·George A BubenikGlen J van der Kraak
Feb 24, 2010·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·A FraserR J Rosengren
Jun 1, 2011·Cell and Tissue Research·Masahiko TakahataEdward M Schwarz
Dec 19, 2012·Actas urologicas españolas·J Torremadé-BarredaE Franco-Miranda
Feb 26, 2013·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Antonio CabalTomohiro Ishikawa
Nov 12, 2013·Journal of Ethnopharmacology·Sung-Hui TsengChing-Chiung Wang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.