Relationship between weight change in young adulthood and the risk of NIDDM. The Sotetsu Study

Diabetes Care
Y SakuraiK Nakamura

Abstract

To investigate the independent effect of weight change in young adulthood on the risk of prevalent NIDDM among middle-aged Japanese men. A case-control study was carried out in 895 male employees aged > or = 30 years of a railway company located in the vicinity of Tokyo. Adjusted odds ratios (ORs) were calculated for prevalent diabetes in each category of weight change (obtained from subjects' medical records) in young adulthood and adulthood. Adjustment for current age, initial BMI, and weight change in each age stratum was performed by the Mantel-Haenszel method or multiple logistic regression analysis. Weight change between 20 years of age and the age at maximum weight was not associated with the risk of NIDDM. Weight gain between 20 and 25 years of age was significantly and positively associated with the risk of NIDDM (OR 3.87 for gains > or = 10.0 kg, 2.53 for gains of 5.0-9.9%, and 3.73 for gains > or = 10.0%). On the other hand, moderate weight gain after 30 years of age was significantly inversely associated with NIDDM (OR 0.44 for gains of 5.0-9.9 kg, 0.15 for gains of 10.0-19.9%, and 0.38 for gains of 20.0-29.9%). Extreme weight gain between 20 and 25 years of age is a significant predictor of NIDDM, independent of cu...Continue Reading

Citations

Jan 1, 1991·International Archives of Occupational and Environmental Health·K TeruyaY Kaneko
Jul 27, 2007·Administration and Policy in Mental Health·Nancy H CovellSusan M Essock
May 30, 2002·Life Sciences·Martina C M Ryan, Jogin H Thakore
May 15, 1998·Journal of Women's Health·S C Finn
Jul 13, 2000·Journal of Epidemiology and Community Health·H E ResnickX Lin
Aug 20, 2005·Diabetic Medicine : a Journal of the British Diabetic Association·E BlackT I A Sørensen
Oct 30, 2013·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·S KodamaH Sone
Sep 1, 2000·Obesity Research·M FogelholmS Sarna

❮ Previous
Next ❯

Related Concepts

Related Feeds

American Diabetes Association Journals

Discover the latest diabetes research published by the journals from the American Diabetes Association.