Relationship between zinc parameters and either body weight gain, protein intake or survival time in zinc-deficient rats

Journal of Nutritional Science and Vitaminology
Takafumi Norii

Abstract

This study was undertaken to examine the relationships between zinc parameters (serum alkaline phosphatase activity, and zinc concentration in serum and femur) and either body weight gain, protein intake or survival time in zinc deficient rats. Demineralized soy protein (DP) and alkali-treated soy protein (AP) were used as dietary protein sources in order to make zinc deficient diets (< 0.5 mg zinc/kg diet). The same diets (DP and AP diets) supplemented with lysine or cystine were also given freely to rats. Moreover, in other experiments, the above relationships were examined. During the early stages, a significant negative correlation between body weight gain and survival time in zinc-deficient rats was demonstrated. The significant negative correlation coefficient between protein intake and survival time increased gradually, and the maximum value of this correlation coefficient was higher than that between body weight gain and survival time. The significant correlations between protein intake and femur zinc concentration were recognized throughout the longer periods. These results show that the number of zinc-deficient rats which survive decreases as protein intake increases throughout the feeding period, that the influence o...Continue Reading

Citations

Nov 1, 2011·Biological Trace Element Research·Takafumi Norii
Oct 7, 2010·Journal of Nutritional Science and Vitaminology·Takafumi Norii
Oct 24, 2007·The Journal of Biological Chemistry·Liping HuangKent K C Lloyd

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