PMID: 6109285Nov 1, 1980Paper

Relationship of biosynthesis of slow reacting substance to intracellular glutathione concentrations

Proceedings of the National Academy of Sciences of the United States of America
C W ParkerH J Wedner

Abstract

To further elucidate the role of glutathione (GSH) in the biosynthesis of slow reacting substance (SRS), SRS generation was studied in rat basophilic leukemia cells that had been preincubated with 2-cyclohexen-1-one or diethyl maleate to decrease their intracellular GSH concentrations. At low GSH levels SRS formation was markedly inhibited. The formation of other lipoxygenase products was much less affected, although some decrease in 5-hydroxyicosatetraenoic acid formation also occurred, apparently due in part to less rapid reduction of the 5-hydroperoxide.

References

Oct 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·B A JakschikC W Parker
Sep 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·R C MurphyB Samuelsson
Nov 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·O W Griffith, A Meister
Aug 28, 1979·Biochemical and Biophysical Research Communications·N A PorterH Weenen
Aug 28, 1979·Biochemical and Biophysical Research Communications·C W ParkerS F Falkenhein
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May 1, 1980·Prostaglandins·B Samuelsson, S Hammarström

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Citations

Jul 1, 1982·Chemico-biological Interactions·R Reiter, A Wendel
Sep 1, 1984·The Journal of Allergy and Clinical Immunology·C W Parker
Apr 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·C A RouzerZ A Cohn
Feb 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·M E AndersonA Meister
Dec 1, 1987·The International Journal of the Addictions·M D NewcombB Fahy
Oct 1, 1990·Clinical Biochemistry·P Borgeat, P H Naccache
Feb 15, 1984·Biochemical Pharmacology·M K Bach
Jan 1, 1981·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·B K Siesjö
Apr 2, 2009·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Sebastian van de LindeMarkus Sauer
Jan 1, 1984·Acta Psychiatrica Scandinavica. Supplementum·B K Siesjö
Sep 15, 1982·International Journal of Cancer. Journal International Du Cancer·D M ThomsonM K Bach
Dec 21, 2017·Metallomics : Integrated Biometal Science·A LaM C Linder

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