Relationship of blood pressure control and hospitalization risk to medication adherence among patients with hypertension in Taiwan

American Journal of Hypertension
Pin-Hsuan WuChih-Ching Chang

Abstract

Despite the efficacy of antihypertensive treatment in preventing cardiovascular complications, there are often problems with medication adherence in hypertensive patients. The objective of this study was to examine the medication adherence and its association with blood pressure (BP) control, cardiovascular disease (CVD) hospitalization, and all-cause hospitalization. We conducted a retrospective cohort observation of patients who were treated for hypertension from January 2005 to December 2006. Medical and pharmacy claims were obtained from Taiwan's National Health Insurance (NHI) database, whereas electronic records, including demographic characteristics and clinical information, were retrieved from a disease management program. To determine the degree of medication adherence, we calculated the proportion of days covered (PDC) by filled prescriptions. The associations of medication adherence with BP control, CVD hospitalization, and all-cause hospitalization were examined using multiple logistic regression models. The study subjects comprised a total of 29,685 hypertensive patients. Of which, 40.1% of the patients had hypertension history of >5 years and 39.7% of patients had some comorbidity. In total, 85.5% of patients were...Continue Reading

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