PMID: 8581780Sep 1, 1995Paper

Relationship of co-morbidities of obesity to weight loss and four-year weight maintenance/rebound

Obesity Research
D D HensrudG R Hunter

Abstract

This study examined the effect of weight loss (separate from energy restriction) and weight maintenance/rebound over time on blood pressure, serum lipids, and body composition in 24 obese (mean 137% ideal body weight (IBW)) females with mild to moderate hypertension. Weight loss was induced under tightly controlled General Clinical Research Center conditions until each subject had lost at least 10 kg (mean 13 kg) and attained normal body weight (< 120% IBW). After 4 years subjects returned for repeat evaluation. Weight changes were compared with 24 pair-matched normal weight controls who were also followed for 4 years. With weight loss, significant improvements were seen in standing mean arterial pressure (MAP), serum total cholesterol, low-density lipoprotein cholesterol, and triglycerides. Subjects regained 11 kg (87% of the weight lost) over the 4 year follow-up period while control subjects gained only 2 kg. Subjects who chose self-selected exercise gained less weight than nonexercisers (6 kg vs. 13 kg, P < 0.05). With weight regain there were significant increases in standing and supine MAP, total cholesterol, and high-density lipoprotein (HDL) cholesterol. The amount of weight regained was significantly correlated with st...Continue Reading

References

May 1, 1992·Journal of Clinical Epidemiology·B Arroll, R Beaglehole
Jul 1, 1992·The American Journal of Clinical Nutrition·R L WeinsierA A Bartolucci
Sep 1, 1991·Diabetes Care·R R Henry, B Gumbiner
May 1, 1989·The American Journal of Clinical Nutrition·K N PavlouW P Steffee
Oct 30, 1987·The American Journal of Cardiology·G L Blackburn, B S Kanders
Jul 1, 1986·The British Journal of Nutrition·G B ForbesB A Lipinski
Jul 1, 1969·Journal of Applied Physiology·J H Wilmore
Jan 1, 1981·The American Journal of Medicine·E A RichterS H Schneider
Sep 26, 1963·Annals of the New York Academy of Sciences·J BROZEKA KEYS

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Citations

Mar 23, 2000·Eating and Weight Disorders : EWD·S Sarlio-Lähteenkorva, A Rissanen
Jun 19, 2007·American Journal of Preventive Medicine·Edward C WeissMary K Serdula
Jun 19, 2001·Cardiology in Review·K J MelansonP F Wilson
Apr 25, 2001·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·M R LoweS Phelan
Dec 28, 1999·Public Health Nutrition·M A van Baak
Apr 25, 2000·American Journal of Hypertension·I Ben-DovM Gaides
Apr 8, 2004·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Kevin P Davy, John E Hall

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