PMID: 9545019Apr 17, 1998Paper

Relationship of leptin concentration to gender, menopause, age, diabetes, and fat mass in African Americans

Obesity Research
A E SumnerR V Considine

Abstract

This investigation was designed to determine the relationship of leptin concentration to gender, sex hormones, menopause, age, diabetes, and fat mass in African Americans. Participants included 101 African Americans, 38 men (mean age, 34.2 +/- 7.4 years), 29 age-matched premenopausal women (mean age, 32.6 +/- 3.7 years), and 36 postmenopausal women (mean age, 57.8 +/- 5.9 years). The women were not taking exogenous sex hormones, and 12 subjects were diabetic. Percent body fat was calculated with the Siri formula, fat mass (FM) was calculated as weight x percent body fat, and Fat-free mass (FFM) was calculated as weight minus FM. Fasting plasma was assayed for leptin, estradiol, free testosterone, glucose, and insulin concentrations. The nondiabetics had an oral glucose tolerance test (OGTT). The diabetics compared with the non-diabetics had a higher central fat index (p=0.04) but otherwise were similar to nondiabetics in all parameters measured. Body mass index, percent body fat, and FM were greater in women than men (p<0.001). Leptin concentrations in men, premenopausal, and postmenopausal women were: 7.51 +/- 8.5, 33.9 +/- 17.3, 31.4 +/- 22.3 ng/mL. Leptin/FM x 100 in the three groups were: 28.9 +/- 16.1, 98.65 +/- 44.9, 77.1...Continue Reading

Associated Clinical Trials

References

Sep 1, 1995·Nature Medicine·F LönnqvistM Schalling
Jul 28, 1995·Science·M A PelleymounterF Collins
Feb 1, 1996·The New England Journal of Medicine·R V ConsidineT L Bauer
Sep 1, 1996·Nature Medicine·P J HavelS D Phinney
Oct 1, 1996·Biochemical and Molecular Medicine·M S HickeyJ F Caro
Nov 1, 1996·The Journal of Clinical Endocrinology and Metabolism·R E OstlundR Gingerich
Dec 1, 1996·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·F HubeH Hauner
Dec 1, 1996·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·M TakahashiY Matsuzawa
Aug 1, 1997·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·R VettorR Pasquali

❮ Previous
Next ❯

Citations

Apr 12, 2000·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·A VerrottiF Chiarelli
Apr 9, 2013·Psychological Medicine·G KohlboeckUNKNOWN LISA-plus stuStudy Group
Jul 1, 1999·Clinical and Experimental Pharmacology & Physiology·T OkazakiM Ikeda
Oct 16, 2010·Metabolic Syndrome and Related Disorders·Pavani Bandaru, Anoop Shankar
Feb 12, 2009·Infectious Agents and Cancer·Camille C RaginEmanuela Taioli
Sep 21, 2013·Annals of Surgical Oncology·Jennifer L GnerlichSusan E Crawford
Sep 20, 2005·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Radka LichnovskáJirí Hrebícek
Sep 17, 2008·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Martin PetzelKristian Safarcik
Feb 11, 2010·Journal of Atherosclerosis and Thrombosis·Sofia G SpiroglouHelen H Papadaki
May 7, 2010·Journal of Medical Primatology·Richard G Bribiescas, Stephanie F Anestis
Feb 26, 2013·The Journal of Pediatrics·Melanie RankMartin Halle
Oct 6, 2016·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Rabia FarooqSabhiya Majid
Aug 9, 2003·Japanese Heart Journal·Abdulkerim BedirNurol Arik
Jun 7, 2003·Nutrition and Cancer·Gina Day Stephenson, David P Rose
Feb 2, 2008·Obesity·Robert V ConsidineAnne E Sumner
Apr 8, 2003·The Journal of Clinical Endocrinology and Metabolism·Nicola PannacciulliGiovanni De Pergola
May 26, 2006·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Grazyna Bednarek-TupikowskaAndrzej Milewicz
Aug 31, 2017·International Journal of Obesity : Journal of the International Association for the Study of Obesity·S HunmaA G Dulloo
Mar 11, 2003·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·C Di CarloC Nappi
Sep 11, 2001·The Journal of Clinical Endocrinology and Metabolism·C A LissettS M Shalet
Jul 21, 2000·The Journal of Clinical Endocrinology and Metabolism·M B HorlickR L Leibel
Feb 23, 2021·Archives of Physiology and Biochemistry·Amani S Alomari, Rowyda N Al-Harithy
Mar 5, 2021·Journal of the Chinese Medical Association : JCMA·Usha AdigaSudhindra Rao

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.