Relationship of lipoproteins, apolipoproteins, triglycerides and lipid ratios to plasma total cholesterol in young adults: the CARDIA Study. Coronary Artery Risk Development in Young Adults

Journal of Cardiovascular Risk
C IribarrenS Sidney

Abstract

To characterize the association of carrier lipoproteins, apolipoproteins, triglycerides and various lipid ratios with total cholesterol in young adults. Cross-sectional data from the baseline examination (1985-1986) of The Coronary Artery Risk Development In Young Adults (CARDIA) Study, a multicenter investigation of a biracial cohort of 4941 men and women aged 18-30 years. Multiple linear regression models to estimate mean levels of lipids and lipoproteins for each category of total cholesterol, stratified by race and sex and adjusted for age and education level. As expected, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), apolipoprotein B (ApoB), apolipoprotein A-1 (ApoA-1) and triglycerides increased linearly with the level of total cholesterol in all race-sex subgroups. The LDL-C/HDL-C, ApoB/ApoA-1 and LDL-C/ApoB ratio also increased with total cholesterol in all race-sex subgroups. The HDL-C/ApoA-1 ratio, indicative of cholesterol content per HDL particle, did not vary with total cholesterol except in white men, in whom it was slightly lower for those with high total cholesterol than those with low total cholesterol concentrations. White men showed higher triglyceride concentratio...Continue Reading

Citations

May 26, 2001·The American Journal of Cardiology·H N Ginsberg
Oct 22, 2003·Archives of Medical Research·Segundo MoránMisael Uribe
Apr 25, 2014·European Journal of Endocrinology·You-Cheol HwangCheol-Young Park

❮ Previous
Next ❯

Related Concepts

Related Feeds

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.