Relationship of long noncoding RNA and viruses

Genomics
Yao-zhong DingYong-guang Zhang

Abstract

Long noncoding (lnc)RNAs comprise a diverse group of transcripts including large intervening noncoding (linc)RNAs, natural antisense transcripts (NATs) and intronic lncRNAs. The functions and mechanisms of more than 200 lncRNAs have been studied in vitro and the results suggest that lncRNAs may be molecular markers of prognosis in cancer patients. Some lncRNAs can promote virus replication and allow escape from cytosolic surveillance to suppress antiviral immunity. For example, lncRNA can cause persistent infection by Theiler's virus, and microRNA (miR)-27a/b is important for efficient murine cytomegalovirus (MCMV) replication. The available evidence suggests that lncRNAs may be potential targets of novel antiviral drugs.

References

Feb 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·M R LernerJ A Steitz
Jan 10, 2002·Nature Genetics·Anton WutzRudolf Jaenisch
Dec 6, 2002·Nature·Y OkazakiUNKNOWN RIKEN Genome Exploration Research Group Phase I & II Team
Jun 7, 2005·Nature Cell Biology·Jidong LiuRoy Parker
Jul 15, 2005·Journal of Virology·M Gunnar AnderssonGöran Akusjärvi
Aug 23, 2005·Gene·Fabrício F Costa
Apr 1, 2006·Proceedings of the National Academy of Sciences of the United States of America·Melanie R GingerJeffrey M Rosen
Jan 6, 2007·International Journal of Cancer. Journal International Du Cancer·Shengyong YinJianren Gu
Jan 11, 2007·Genes & Development·Kannanganattu V Prasanth, David L Spector
May 19, 2007·The EMBO Journal·Yoon Ki KimLynne E Maquat
Feb 5, 2008·Cancer Cell·Zhen Fan YangSheung Tat Fan
May 21, 2008·Nature Reviews. Genetics·Christopher S Sullivan
Oct 8, 2008·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Paulo P Amaral, John S Mattick
Dec 6, 2008·Science·Amy C SeilaPhillip A Sharp
Feb 4, 2009·Nature Reviews. Genetics·Tim R MercerJohn S Mattick
Feb 26, 2009·Cell·Chris P PontingWolf Reik
Feb 26, 2009·Cell·Melissa J Moore, Nick J Proudfoot
Apr 25, 2009·PLoS Genetics·John S Mattick
Jul 3, 2009·Genes & Development·Jeremy E WiluszDavid L Spector
Oct 5, 2010·Cell·Ulf Andersson ØromRamin Shiekhattar
Mar 10, 2011·Nature Medicine·Hans Clevers
Aug 2, 2011·Cell·Leonardo SalmenaPier Paolo Pandolfi
Oct 13, 2011·Nature Reviews. Genetics·Mary Muers
Feb 24, 2012·Cell Research·Dean G Tang
Apr 12, 2012·Nucleic Acids Research·Victoria A MoranAhmad M Khalil

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Citations

May 31, 2018·Archives of Microbiology·Yao-Zhong DingYong-Guang Zhang
Oct 11, 2017·The American Journal of Tropical Medicine and Hygiene·Xiao-Jun WangHong-Juan Peng
Apr 2, 2020·Frontiers in Cellular and Infection Microbiology·Shuang LuWei Hou
Mar 30, 2020·The Journal of Infectious Diseases·Antón Vila-SanjurjoMariana Leguia
Mar 8, 2020·Journal of Biomedical Science·Mel Campbell, Yoshihiro Izumiya
Jun 13, 2017·Frontiers in Cellular and Infection Microbiology·Weiwei Liu, Chan Ding
May 30, 2020·International Journal of Molecular Sciences·Lea DenzerChristian Schwerk
Jul 13, 2021·Reviews in Medical Virology·Mina Mobini KeshehSomayeh Shokri

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