Relationship of myocardial ischemia and injury to coronary artery disease in patients with supraventricular tachycardia

The American Journal of Cardiology
Radhika Nandur BukkapatnamUma Narasimhan Srivatsa

Abstract

Increase of serum troponin I and ST-segment depression are objective markers of myocardial ischemia/injury. Abnormalities of the 2 indicators have been associated with supraventricular tachycardia (SVT) but their relevance for diagnosing acute coronary syndrome and the presence of coronary artery disease (CAD) in this setting have not been clarified. Therefore, we sought to evaluate the frequency of CAD based on increased troponin I and ST-segment depression during SVT. During a 5-year period, 104 patients were admitted with a diagnosis of SVT, 80 of whom had troponin I testing, and 70 of these patients could be assessed for ST-segment changes. Thirty-seven patients (48%) had increased troponin I (mean 1.54 +/- 2.7 ng/dl, normal <or=0.07 ng/dl) and 46 patients (57%) had ST-segment depression >or=1.0 mm. There were no significant differences in baseline characteristics and clinical presentation of patients with and without troponin I increase or ST-segment depression. There was no difference in the diagnosis of CAD by noninvasive or invasive testing in patients with and without increased troponin I. More patients with than without ST-segment depression had evidence of CAD (22% vs none, p = 0.01), but after adjusting for covariat...Continue Reading

References

Aug 1, 1988·Journal of the American College of Cardiology·S D NelsonF Morady
May 1, 1993·Japanese Heart Journal·K TakayanagiY Takabatake
Nov 5, 2002·Internal Medicine Journal·T K BakshiG P Armstrong
Jan 31, 2004·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Michael C KontosJames L Tatum
Jul 12, 2005·International Journal of Cardiology·D P RedfearnM J Griffith
Nov 18, 2005·International Journal of Cardiology·Nitin MahajanEdgar Lichstein
Jun 15, 2007·Journal of Cardiovascular Pharmacology and Therapeutics·Marc DorenkampChristian Sticherling
Oct 2, 2007·The American Journal of Medicine·Melissa R RobinsonEzra A Amsterdam

❮ Previous
Next ❯

Citations

Dec 21, 2010·European Heart Journal·S AgewallH Katus
Jul 21, 2015·International Journal of Cardiology·Béatrice Brembilla-PerrotNicolas Girerd
Apr 9, 2014·Emergency Medicine Australasia : EMA·Atifur Rahman, Simon A Broadley
Jan 27, 2015·Current Atherosclerosis Reports·Nathaniel R SmilowitzSteven P Sedlis
Aug 31, 2016·International Journal of Cardiology·Alaa AlghamryChristopher Tan
Mar 21, 2017·Emergency Medicine Australasia : EMA·Aadith AshokDavid McD Taylor
Jun 11, 2017·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Thomas A DewlandGregory M Marcus
Dec 23, 2019·The American Journal of Emergency Medicine·Brit LongAlex Koyfman
Jun 12, 2021·Vascular Health and Risk Management·Aleksey Chaulin
Aug 28, 2021·Journal of Clinical Medicine·Chieh-Ching YenChip-Jin Ng

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Diseases: Risk Factors

Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.