Relationship of primary immune thrombocytopenic purpura and atopia among children: a case control study.

Scientific Reports
Gholamreza BahoushMarzieh Nojomi

Abstract

Atopic dermatitis (AD) is a chronic disease affecting 10-30% of children and 2-10% of adults worldwide. It is manifested by the pruritus eczema lesions on the skin. Immune thrombocytopenic purpura (ITP) is the most common cause of acute onset of thrombocytopenia in childhood. The aim of this study was association of primary immune thrombocytopenic purpura and atopia among children. This case control study was performed on patients with acute and chronic ITP who were confirmed by a hematologist. The control group was also selected from the siblings of the patients who were healthy and almost matched by age and sex with the patient group. Data were entered into a questionnaire under the SPSS-20 program, and demographic data were analyzed descriptively. In the present study, 120 patients were enrolled, 60 of whom were in the patient group and 60 in the control group. Mean age was 95 and 98 months for patients and control. This study showed a significant association of ITP with allergic rhinitis (P = 0.02), atopic dermatitis (P = 0.004), itching (P = 0.042), and dry skin (P = 0.015). However, no significant relationship was found between ITP and asthma (P-value = 0.18). This study does not reveal the causality between atopy and ITP...Continue Reading

References

Aug 23, 2008·The Journal of Investigative Dermatology·Jon M Hanifin
Oct 3, 2008·Pediatrics·Andrew C KrakowskiMagdalene A Dohil
Jun 3, 2011·Cleveland Clinic Journal of Medicine·Keith McCrae
Apr 1, 2008·The World Allergy Organization Journal·Hugo P Van BeverBee Wah Lee
May 15, 2013·Asia Pacific Allergy·Kyu Han Kim
May 29, 2013·Allergology International : Official Journal of the Japanese Society of Allergology·Donald Y M Leung
Jul 10, 2014·ISRN Allergy·Simon Francis Thomsen
Jan 13, 2015·Pediatric Research·Ming-Ru ChiangChia-Hung Kao
May 6, 2015·Asia Pacific Allergy·Aravind Yadav, Rakesh Naidu
Jan 8, 2016·Balkan Medical Journal·Anıl TombakMehmet Ali Sungur
Jun 6, 2018·Current Treatment Options in Allergy·Amy HuangKanwaljit Brar
Oct 3, 2018·Pediatric Blood & Cancer·Paola GiordanoMaria Felicia Faienza
Nov 25, 2018·Allergology International : Official Journal of the Japanese Society of Allergology·Yuka OkuraIchiro Kobayashi

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Related Feeds

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Related Papers

American Journal of Hematology
Şinasi Özsoylu
Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Mahmoud H AyeshAbdullah Kasasbeh
Seminars in Thrombosis and Hemostasis
T Kühne, P Imbach
American Journal of Diseases of Children
R H Tomar, M J Stuart
© 2021 Meta ULC. All rights reserved