Relationship of stimulated whole saliva cortisol level with the severity of a feeling of dry mouth in menopausal women

Gerodontology
Farzaneh Agha-HosseiniN Mirjalili

Abstract

To evaluate the relationship of stimulated whole saliva cortisol level with the severity of a feeling of dry mouth (DM) in menopausal women. A feel of DM is a major complaint for many elderly individuals and strongly associated with the menopause. The exact mechanisms that mediate sensation of DM in menopausal women have not been firmly established. A case-control study was carried out on 104 selected menopausal women with/without a feeling of DM, conducted at the Clinic of Oral Medicine, Tehran University of Medical Sciences. Xerostomia Inventory (XI) score was used as an index of DM severity. Stimulated whole saliva cortisol concentration (stimulated by chewing standard-sized paraffin for 60 s) was measured by ELISA. Statistical analysis by Student's t-test and Spearman correlation was used. The mean cortisol concentration of saliva, but not saliva cortisol output, was significantly higher in the cases than in the controls. There was significant positive correlation between XI score and concentration (r = 0.357, p = 0.000) or output (r = 0.223, p = 0.017) of stimulated whole saliva cortisol. It appears that stimulated whole saliva cortisol is high in menopausal women with a feeling of DM.

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Citations

Jun 18, 2011·Clinical Oral Investigations·Iraj Mirzaii-DizgahMohammad Mohsen Salehi
Jun 7, 2013·Aging Clinical and Experimental Research·Farzaneh Agha-HosseiniNargess Mirjalili
Feb 2, 2013·Clinical and Translational Medicine·Roslinda MohamedChamindie Punyadeera
Oct 12, 2013·Annals of Medical and Health Sciences Research·P DuttP Kumar
Jan 21, 2015·Acta Odontologica Scandinavica·Marlene ChevalierValerie Pouyssegur-Rougier
Sep 16, 2014·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Marília Leal Ferreira LagoLuciane Maria Oliveira Brito
Dec 20, 2015·Singapore Dental Journal·Ngo Di Ying Joanna, William Murray Thomson
Feb 26, 2013·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Farzaneh Agha-HosseiniIraj Mirzaii-Dizgah
Sep 30, 2018·Journal of Prosthodontic Research·Moe KosakaKeiichi Sasaki
Sep 27, 2019·International Journal of Molecular Sciences·Pingping Han, Sašo Ivanovski
Sep 24, 2020·Journal of Oral Rehabilitation·Hitomi Ono MinagiTakayoshi Sakai
Nov 17, 2019·Medical Hypotheses·Mohammad-Hossein Mirzaii-DizgahIraj Mirzaii-Dizgah
Dec 22, 2011·The Journal of Contemporary Dental Practice·Iraj Mirzaii-Dizgah, Farzaneh Agha-Hosseini
Oct 14, 2014·The Journal of Contemporary Dental Practice·Behnoosh Vasaghi-Gharamaleki, Iraj Mirzaii-Dizgah
Jun 21, 2021·Revista española de cirugía ortopédica y traumatología·M-R Mirzaii-DizgahB Forogh
Sep 29, 2021·Clinical Oral Investigations·Hitomi Ono MinagiTakayoshi Sakai

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