Relationship of the ORBIT and HAS-BLED scores with Killip class 3-4 in patients with ST-segment elevation myocardial infarction

Medicine
Qing ZhangHui-He Lu

Abstract

Heart failure (HF) complicating ST-segment elevation myocardial infarction (STEMI) is recognized as an ominous complication. The HAS-BLED and Outcomes Registry for Better Informed Treatment (ORBIT) scores are used to assess the bleeding risk in patients with anticoagulated atrial fibrillation. This study aimed to investigate the relationship of the ORBIT and HAS-BLED scores with Killip class 3-4 in patients with STEMI.639 patients with STEMI were enrolled in this study. The ORBIT and HAS-BLED scores were recorded after admission, and all patients were divided into 2 groups: the Killip class 1-2 and Killip class 3-4 groups. Different clinical parameters were compared. The predictive values of the ORBIT and HAS-BLED scores for Killip classes 3 to 4 were assessed using receiver-operating characteristic (ROC) analyses. Univariate and multivariate logistic analyses were used to evaluate the relationships between variables and Killip class 3-4.The ORBIT and HAS-BLED scores were higher in the Killip class 3-4 group than in the Killip class 1-2 group (P < .05). The areas under the ROC curve of the ORBIT and HAS-BLED scores for predicting the higher Killip classification were 0.818 (95% CI: 0.786-0.847, P < .0001) and 0.674 (95% CI: 0.6...Continue Reading

References

Oct 1, 1967·The American Journal of Cardiology·T Killip, J T Kimball
Jan 13, 2004·Journal of the American College of Cardiology·Daniel E FormanHarlan M Krumholz
Jan 28, 2004·Circulation·Philippe Gabriel StegUNKNOWN Global Registry of Acute Coronary Events Investigators
Sep 1, 2004·Journal of the American College of Cardiology·G Michael FelkerChristopher M O'Connor
Sep 24, 2004·The New England Journal of Medicine·Nagesh S AnavekarMarc A Pfeffer
Mar 15, 2008·European Heart Journal·Yoram AmsalemJonathan Leor
Aug 10, 2010·American Heart Journal·Stefano MuzzarelliUNKNOWN TIME-CHF Investigators
Feb 16, 2015·The American Journal of Cardiology·Leonardo P de CarvalhoMark Y Chan
Dec 15, 2015·International Journal of Cardiology·Luciano Consuegra-SánchezAntonio Melgarejo-Moreno
Apr 4, 2016·International Journal of Cardiology·Katsuya KajimotoUNKNOWN investigators of the Acute Decompensated Heart Failure Syndromes (ATTEND) registry
Aug 2, 2016·JACC. Cardiovascular Interventions·Konstantinos C KoskinasStephan Windecker
Nov 13, 2017·JACC. Heart Failure·Niels Grote BeverborgPeter van der Meer

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