PMID: 9431857Feb 12, 1998Paper

Relationships between changes in left ventricular mass and in clinic and ambulatory blood pressure in response to antihypertensive therapy

Journal of Hypertension
Robert H FagardL Thijs

Abstract

To analyse the relationships between changes in left ventricular mass in response to 6-month antihypertensive therapy and changes in conventional and automated measurements of clinic blood pressure, average 24 h ambulatory blood pressure and daytime and night-time blood pressures. After a placebo run-in period, patients with essential hypertension (World Health Organization stages I-II) were treated for 6 months with one or a combination of two first-line antihypertensive drugs. Investigations included echocardiography, conventional and automated clinic blood pressure measurements and ambulatory blood pressure monitoring. Daytime and night-time blood pressures were assessed according to two clock-time-dependent and two clock-time-independent methods, with a wide and a narrow approach for each technique. Fifty-four patients completed the 6-month treatment period. Left ventricular mass, adjusted for sex and body size, was correlated significantly to systolic and diastolic clinic blood pressures, both before (r = 0.57 and r = 0.48, P < 0.001) and during antihypertensive therapy (r = 0.43, P < 0.001 and r = 0.27, P < 0.05). Changes in left ventricular mass were significantly related to changes in blood pressure. The correlation coe...Continue Reading

Associated Clinical Trials

References

Jan 1, 1992·Hypertension·A StantonE O'Brien
Feb 15, 1986·The American Journal of Cardiology·R B DevereuxN Reichek
Jan 1, 1984·European Journal of Clinical Pharmacology·L A FerraraG Vallone
Jul 1, 1995·American Journal of Hypertension·T G Pickering
Aug 1, 1993·American Journal of Hypertension·R FagardA Amery
Oct 1, 1995·The Netherlands Journal of Medicine·R H Fagard
May 15, 1996·JAMA : the Journal of the American Medical Association·R E SchmiederA Klingbeil

❮ Previous
Next ❯

Citations

Jul 18, 2000·Occupational and Environmental Medicine·J A StaessenR H Fagard
Mar 24, 2007·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Hideyuki Uno, Kazuomi Kario
Nov 24, 2004·American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions·Paolo Verdecchia, Fabio Angeli
Feb 26, 2013·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Mathew J GregoskiFrank A Treiber
Mar 25, 2004·Clinical and Experimental Hypertension : CHE·Yasuko OkanoSatoshi Umemura
Jul 22, 2008·The American Journal of Cardiology·Lori B CroftMartin E Goldman
Nov 30, 2007·The Journal of Clinical Hypertension·Dimitris P Papadopoulos, Thomas K Makris
Nov 30, 2011·Acta Obstetricia Et Gynecologica Scandinavica·Philippe H J HoogstederLouis L Peeters
Mar 8, 2014·Annals of Occupational and Environmental Medicine·Bongkyoo ChoiDean Baker
Aug 27, 2013·Journal of the American College of Cardiology·David E Kandzari, Paul A Sobotka
Apr 21, 2016·The Journal of Clinical Hypertension·Iris KistnerRoland E Schmieder
Sep 26, 2003·Psychosomatic Medicine·Patrick R SteffenAndrew Sherwood
Jul 5, 2013·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Ioannis AndrikouChristodoulos Stefanadis
Nov 18, 2000·Hypertension·G Mancia, G Parati
Apr 4, 2007·Hypertension·Gary L SchwartzStephen T Turner
Jan 28, 2006·Respiration; International Review of Thoracic Diseases·Wojciech MyslinskiGerhard Schultze-Werninghaus
Sep 14, 2013·Journal of Hypertension·Eoin O'BrienUNKNOWN European Society of Hypertension Working Group on Blood Pressure Monitoring
Aug 4, 2001·Psychosomatic Medicine·P R SteffenA Sherwood
Jun 11, 2002·Blood Pressure Monitoring·J A StaessenUNKNOWN Participants of the 2001 Consensus Conference on Ambulatory Blood Pressure Monitoring
Jul 28, 1999·Clinical and Experimental Hypertension : CHE·G ManciaA Zanchetti
Aug 11, 2001·American Journal of Hypertension·A SherwoodA L Hinderliter
Feb 28, 2002·American Journal of Hypertension·Andrew SherwoodAlan L Hinderliter
Oct 3, 2001·Medicine and Science in Sports and Exercise·P R SteffenJ A Blumenthal
Apr 8, 2009·Journal of Hypertension·Ramiro A SanchezUNKNOWN Latin America Expert Group
Apr 23, 2021·International Journal of Cardiology. Hypertension·Oscar HägglundJan Östergren
Oct 5, 2007·Revista española de cardiología·UNKNOWN Grupo de Trabajo para el Tratamiento de la Hipertensión Arterial de la Sociedad EuropeaJosé Luis Zamorano

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.